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Trifluridine
go.drugbank.com/drugs/DB00432ApprovedInvestigationalIt is an active antiviral agent in ophthalmic solutions used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus. … The combination product of trifluridine with tipiracil marketed as Lonsurf has been approved in Japan, the United States, and the European Union for the treatment of adult patients with metastatic colorectal
Mixtures: LONSURF FILM-COATED TABLET 20 MG/8.19 MG, LONSURF FILM-COATED TABLET 20 MG/8.19 MGProducts: THILO %1 GÖZ DAMLASI, 5 MLReserpine
go.drugbank.com/drugs/DB00206ApprovedWithdrawnThe FDA withdrew its approval for the use of all oral dosage form drug products containing more than 1 mg of reserpine.[L43942] … An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Mixtures: REGROTON TABLET, 20 ADET, Ser-Ap-EsInsulin glulisine
go.drugbank.com/drugs/DB01309ApprovedInsulin is an important treatment in the management of Type 1 Diabetes (T1D) which is caused by an autoimmune reaction that destroys the beta cells of the pancreas, resulting in the body not being able … Without treatment or improvement in non-pharmacological measures such as diet and exercise to lower blood glucose, high blood sugar eventually causes cellular resistance to endogenous insulin, and in the
Categories: Drugs Used in DiabetesProducts: APIDRA 100 Units/ml Solution for Injection in vial, APIDRA 100 U/ML- SOLUTION FOR INJECTION IN VIALCantharidin
go.drugbank.com/drugs/DB12328ApprovedInvestigational[A32891, A32892] In 1962 however, marketers of cantharidin failed to produce sufficient efficacy data, resulting in the FDA revision of approval of cantharidin. … and/or keratolytics although various studies have also investigated the possibility of using cantharidin as an inflammatory model or in cancer treatment.
Mixtures: CANTHACUR PS %1,%5,%30 TOPIKAL SOLUSYON 7,5 MLCategories: Compounds used in a research, industrial, or household settingHyaluronidase
go.drugbank.com/drugs/DB14740ApprovedInvestigational[A199047] Hyaluronidase was first used in prescription products in the United States on 5 May 2004.[L13338] … [L13338] The action of hyaluronidase was first described in 1936, and named in 1939.
Products: Wydase Inj 150unit/ml, Wydase Injection Liq 150 Units/mlGlutamic acid
go.drugbank.com/drugs/DB00142ApprovedInvestigationalNutraceuticalA peptide that is a homopolymer of glutamic acid.
Mixtures: PEPZAN 225 MG/225 MG FİLM TABLET, 20 ADET, Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)Patisiran
go.drugbank.com/drugs/DB14582ApprovedPatisiran is a first in class short interfering RNA for the treatment of patients with polyneuropathy caused by hereditary transthyretin-mediated amyloidosis [L4220]. … The approval for Onpattro was granted to Alnylam Pharmaceuticals, Inc. in August of 2018. Onpattro has been granted Fast Track, Priority Review and Breakthrough Therapy, and Orphan Drug designations.
Categories: Compounds used in a research, industrial, or household settingMethionine
go.drugbank.com/drugs/DB00134ApprovedInvestigationalNutraceuticalA sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Mixtures: Aminosyn II 8.5% M In 20% Dextrose (dual Chamber), POLİNUTHREE EN-550 ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ, VE LİPİD EMÜLSİYONU, 2000 MLSynonyms: M, L-a-Amino-g-methylthiobutyric acid2-Ketoglutarate Dehydrogenase Complex Deficiency
smpdb.ca/view/SMP0000549Diseaseoxoglutarate dehydrogenase complex (OGDC). … 2-Ketoglutarate dehydrogenase complex deficiency, also known as alpha-ketoglutarate dehydrogenase deficiency or oxoglutaric aciduria, is an autosomal recessive disorder of the Krebs cycle caused by a defective
Enzymes: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrialBesifloxacin
go.drugbank.com/drugs/DB06771ApprovedFDA approved on May 28, 2009.
Products: BESIVANCE % 0,6 OFTALMIK SÜSPANSIYON, 5 ML