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Displaying results 2061 - 2070 of 10000 in total
  1. Drug

    Alcloxa

    go.drugbank.com/drugs/DB11205
    Approved

    Mixtures: Hae Yan Tooth, BIS II Tooth
  2. Drug

    Albiglutide

    go.drugbank.com/drugs/DB09043
    ApprovedInvestigationalWithdrawn

    Albiglutide is a glucagon-like peptide-1 agonist (GLP-1) biologic drug indicated in the treatment of type 2 diabetes. It is marketed under the brands Eperzan and Tanzeum by GSK (GlaxoSmithKline). … It is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin. Albiglutide was approved on April 15, 2014 by the FDA.

    Categories: Drugs Used in Diabetes
  3. Drug

    Nicorandil

    go.drugbank.com/drugs/DB09220
    ApprovedInvestigationalWithdrawn

    It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium channels. … Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan.

    International brands: K-CorCategories: Vasodilators Used in Cardiac Diseases
  4. Drug

    Tislelizumab

    go.drugbank.com/drugs/DB14922
    ApprovedInvestigational

    [L50346] It has subsequently been approved for additional cancers in the US and EU. [L49349] … Tislelizumab is a humanized monoclonal IgG4 antibody against programmed death receptor-1 (PD-1).

    Categories: Programmed Death Receptor-1 Blocking Antibody
  5. Drug

    Methenamine

    go.drugbank.com/drugs/DB06799
    ApprovedInvestigationalVet approved

    In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine). … Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane.

    Mixtures: All-In-One UTI Emergency Kit, All-In-One UTI Emergency Kit
  6. Drug

    Quaternium-15

    go.drugbank.com/drugs/DB14198
    Approved

    It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. … Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics.

  7. Target

    G protein-coupled receptor kinase 2

    go.drugbank.com/bio_entities/BE0000341
    TargetHumans

    Such receptor phosphorylation initiates beta-arrestin-mediated receptor internalization, and signaling events leading to their desensitization (PubMed:14976224, PubMed:16179383, PubMed:19306925, PubMed … Also able to mediate phosphorylation-independent desensitization of dopamine receptor DRD2 (By similarity)

    Polypeptides: G protein-coupled receptor kinase 2Synonyms: Beta-adrenergic receptor kinase 1
  8. Target

    Receptor tyrosine-protein kinase erbB-2

    go.drugbank.com/bio_entities/BE0000511
    TargetEnzymeHumans

    Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. … Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding.

    Polypeptides: Receptor tyrosine-protein kinase erbB-2Synonyms: Tyrosine kinase-type cell surface receptor HER2
  9. Target

    Taste receptor type 1 member 3

    go.drugbank.com/bio_entities/BE0000582
    TargetHumans

    Functions as a G protein-coupled receptor and primarily signals through the gustducin heterotrimer (PubMed:40339580). … The sweet taste receptor has lower affinity for natural sugars than for synthetic sweeteners (PubMed:40339580, PubMed:40555359).

    Polypeptides: Taste receptor type 1 member 3Synonyms: Sweet taste receptor T1R3
  10. Target

    Insulin-like growth factor 1 receptor

    go.drugbank.com/bio_entities/BE0000858
    TargetHumans

    Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of multiple substrates, that function as signaling adapter proteins including, the insulin-receptor … Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity.

    Polypeptides: Insulin-like growth factor 1 receptorSynonyms: IGF-I receptor, Insulin-like growth factor I receptor