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Etonogestrel
go.drugbank.com/drugs/DB00294ApprovedInvestigationalEtonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel.
Categories: Hormonal Contraceptives for Systemic UsePeginterferon beta-1a
go.drugbank.com/drugs/DB09122ApprovedInvestigationalIt was originally approved by the FDA in 2014 for subcutaneous use, and was approved for intramuscular use in January 2021. … [A176474,L5792] Peginterferon beta-1a is an interferon therapy used for the management of relapsing forms of MS.
Categories: Compounds used in a research, industrial, or household settingFactor XIII (human)
go.drugbank.com/drugs/DB12909ApprovedInvestigationalFor people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential for management and prevention of bleeding episodes … Factor XIII (human) is a heat-treated, lyophilized concentrate of coagulation factor XIII, an endogenous enzyme responsible for the crosslinking of fibrin and an essential component of the coagulation
Thiabendazole
go.drugbank.com/drugs/DB00730ApprovedVet approvedWithdrawnIt is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential.
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseMethacholine
go.drugbank.com/drugs/DB06709Approved[L31763] In patients with AHR, a lower dose of methacholine is required to induce bronchoconstriction, which forms the basis for the methacholine challenge test to diagnose AHR.
Gallium nitrate
go.drugbank.com/drugs/DB05260ApprovedInvestigational[A17097] GANITE, a product of gallium nitrate previously used to treat cancer-related hypercalcemia, was discontinued from marketing in the US for reasons other than safety or effectiveness.
Mycophenolic acid
go.drugbank.com/drugs/DB01024ApprovedInvestigationalMycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone.
Sutilain
go.drugbank.com/drugs/DB09379ApprovedWithdrawnIt is able to dissolve the intercellular matrix which helps with desquamation.
Interferon gamma-1b
go.drugbank.com/drugs/DB00033ApprovedInvestigationalThe sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray et. al. and not specifically interferon gamma 1b. … Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein.
Lanadelumab
go.drugbank.com/drugs/DB14597ApprovedInvestigationalLanadelumab, also known as DX-2930, is a human IgG1 monoclonal antibody designed for subcutaneous self-injection. … [L4537] It has been granted priority review, breakthrough therapy, and orphan drug designations for rare diseases based on the results of clinical trials.