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Limnetrelvir
go.drugbank.com/drugs/DB21677ExperimentalLimnetrelvir is a small molecule drug. The usage of the INN stem '-trelvir' in the name indicates that Limnetrelvir is a antiviral 3CL protease inhibitor. Limnetrelvir has a monoisotopic molecular weight of 557.17 Da.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A SubstratesSorbitan monolaurate
go.drugbank.com/drugs/DB20157InvestigationalSorbitan monolaurate is a small molecule drug. Sorbitan monolaurate has a monoisotopic molecular weight of 346.24 Da.
Categories: P-glycoprotein inhibitorsEnerisant
go.drugbank.com/drugs/DB20605ExperimentalEnerisant is a small molecule drug. The usage of the INN stem '-isant' in the name indicates that Enerisant is a histamine H3 receptor antagonist. Enerisant has a monoisotopic molecular weight of 398.23 Da.
Categories: P-glycoprotein substratesBesigomsin
go.drugbank.com/drugs/DB20894ExperimentalBesigomsin is a small molecule drug. Besigomsin has a monoisotopic molecular weight of 416.18 Da.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesZolmitriptan
go.drugbank.com/drugs/DB00315ApprovedInvestigationalZolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine. Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesFluorometholone
go.drugbank.com/drugs/DB00324ApprovedInvestigationalA glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersTerfenadine
go.drugbank.com/drugs/DB00342ApprovedWithdrawnIn the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.
Categories: Cytochrome P-450 CYP2C8 Inhibitors, P-glycoprotein inhibitorsClobazam
go.drugbank.com/drugs/DB00349ApprovedIllicitInvestigationalClobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis...
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 SubstratesMefloquine
go.drugbank.com/drugs/DB00358ApprovedMalaria is a protozoan disease that places an enormous burden on human health in endemic areas around the world. The 2020 World Health Organization malaria report indicates a 60% decrease in the global malaria fatality rate between 2000 ...
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSulfadiazine
go.drugbank.com/drugs/DB00359ApprovedInvestigationalVet approvedOne of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates