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Triamcinolone
go.drugbank.com/drugs/DB00620ApprovedInvestigationalVet approved[L8243] In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval[L38973] - for the treatment of patients … Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis.
Mixtures: Aureocort 1 mg/g + 30 mg/g Salbe, ReadySharp-KCategories: Corticosteroids for Systemic Use, Corticosteroids for Systemic Use, PlainPaliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalPaliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006. … Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: INVEGA Sustenna Prolonged Release Suspension for IM Injection 25mg/0.25 ml, INVEGA Sustenna Prolonged Release Suspension for IM Injection 50mg/0.5 mlOfatumumab
go.drugbank.com/drugs/DB06650ApprovedInvestigational[L12753] The FDA subsequently approved ofatumumab for the treatment of RMS on August 20, 2020. … In February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing Authorization Application (MAA), respectively, for ofatumumab for the treatment of RMS in adults.
Products: KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MG/0.4ML, Bonspri 20mg/0.4mL Solution for Injection in Pre-filled syringeCarbetocin
go.drugbank.com/drugs/DB01282ApprovedInvestigationalIt is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus. … Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth.
Synonyms: deamino-2-O-methyltyrosine-1-carbaoxytocin, 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocinProducts: DURATOCIN RTS SOLUTION FOR INJECTION 100 MCG/ML, Pharmidea Carbetocin 100 microgram/ml solution for injectionAlbumin human
go.drugbank.com/drugs/DB00062ApprovedInvestigationalAlso known as _Albuminex_ 5% or 25%, one brand of human serum albumin is prepared from the pooled plasma of US donors in FDA-licensed facilities in the US [F229]. … This is a biosimilar drug to existing human serum albumin and was approved for a biological license at both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101].
Mixtures: Sterile Diluent for Allergenic ExtractProducts: Human Albumin 20% Behring (Low Salt) Solution For Infusion, SK Albumin 20% InjectionInsulin glulisine
go.drugbank.com/drugs/DB01309ApprovedIf left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening … cells that the body is no longer able to produce insulin on its own.
Categories: Drugs Used in Diabetes, Insulins and Analogues for Injection, Fast-ActingProducts: APIDRA 100 U/ML- SOLUTION FOR INJECTION IN VIAL, APIDRA 100 Units/ml Solution for Injection in vialPemetrexed
go.drugbank.com/drugs/DB00642ApprovedInvestigationalIt is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative … Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.[A253907]
Products: PEMIREX FOR INJ. 100 MG, PEMIREX FOR INJ. 500 MGAflibercept
go.drugbank.com/drugs/DB08885ApprovedInvestigational[L47976] An aflibercept biosimilar, Yesafili, was approved for use in the EU in September 2023. … [L47966,L47971] The intravitreal formulation, under the brand name EYELEA, was approved by the FDA for the treatment of retinopathy of prematurity in preterm infants in February 2023 and for the treatment
Products: EYLEA SOLUTION FOR INJECTION IN VIAL 2MG, EYLEA 40MG/ML SOLUTION FOR INJECTION IN VIALStreptokinase
go.drugbank.com/drugs/DB00086ApprovedInvestigationalWithdrawnStreptokinase, is a sterile, purified preparation of a bacterial protein elaborated by group C (beta) -hemolytic streptococci.
Products: Streptokinase Karma 1 500 000 IU Powder for Solution for Infusion, KABIKINASE 1.500.000 UI. POLVO PARA INYECCIONFatty Acid Elongation in Mitochondria
smpdb.ca/view/SMP0000054MetabolicMitochondrial elongation may result in fatty acids up to C16 in length. Fatty acid elongation in mitochondria is essentially the reverse of beta-oxidation for fatty acid oxidation. … In liver and kidney fatty acid elongation operates best in the presence of both NADH and NADPH, whereas in heart and skeletal muscle, only NADH is required.