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Vutrisiran
go.drugbank.com/drugs/DB16699ApprovedInvestigational[A249010] Vutrisiran was approved by the FDA in June 2022. … [A249010] More than 130 TTR mutations have been identified so far,[A249015] but the most common one is the replacement of valine with methionine at position 30 (Val30Met).
Trimethoprim
go.drugbank.com/drugs/DB00440ApprovedInvestigationalVet approvedTrimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial ...
Mixtures: K.B. FAMATE, K.B. FAMATE SUSPENSIONAlanine
go.drugbank.com/drugs/DB00160ApprovedInvestigationalNutraceuticalAlanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle...
Mixtures: Clinimix E, Clinimix EProline
go.drugbank.com/drugs/DB00172ApprovedInvestigationalNutraceuticalProline is one of the twenty amino acids used in living organisms as the building blocks of proteins. Proline is sometimes called an imino acid, although the IUPAC definition of an imine requires a carbon-nitrogen double bond. Proline is...
Mixtures: Clinimix E, Clinimix ETalmapimod
go.drugbank.com/drugs/DB05412InvestigationalTalmapimod is the first-generation oral p38 MAP kinase inhibitor developed by Scios. It has shown to be effective to cure inflammatory diseases such as Rheumatoid Arthritis.
MUC1 Dendritic Cell Vaccine
go.drugbank.com/drugs/DB05477InvestigationalDendritic Cell (DC) Therapy is a newly emerging and potent form of immune therapy that amplifies the actions of the body's own immune system to help fight cancer, AIDS and other serious conditions.
Cod liver oil
go.drugbank.com/drugs/DB11321ApprovedNutraceuticalVet approvedCod liver oil is extracted from the liver of cod fish and mainly consists of omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Also being a rich source of vitamin A and D, cod liver oil can be taken orally ...
Zinc protoporphyrin
go.drugbank.com/drugs/DB03934ExperimentalCategories: Heme Oxygenase (Decyclizing), antagonists & inhibitorsEteplirsen
go.drugbank.com/drugs/DB06014ApprovedInvestigationalEteplirsen was the first treatment for DMD approved by the FDA.[A244925] … Eteplirsen was first approved by the FDA in September 2016 for the treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation of the DMD gene, which codes for dystrophin, that
Ranirestat
go.drugbank.com/drugs/DB05327InvestigationalRanirestat is a structurally novel and stereospecifically potent aldose reductase (AKR1B; EC 1.1.1.21) inhibitor, which contains a succinimide ring that undergoes ring-opening at physiological pH levels