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Nogapendekin alfa
go.drugbank.com/drugs/DB18740ApprovedInvestigational[A263617, A263622] Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which … Nogapendekin alfa is a human IL-15N72D variant.
Categories: Interleukin-15, Receptors, Interleukin-15Synonyms: Human interleukin 15 (72-aspartic acid) (human il-15 n72>d isoform), Superagonist interleukin-15:interleukin-15 receptor alphasu/fc fusion complex alt-803Tilidine
go.drugbank.com/drugs/DB13787InvestigationalMixtures: TILIDIN 150/12RETARD 1A PH, TILIDIN 150/12RETARD 1A PHCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesCapsaicin
go.drugbank.com/drugs/DB06774ApprovedInvestigationalCapsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements
Mixtures: NuDroxiPAK M-15, THERMO SULIDIN %1 + %0,025 LIKIT JEL, 50 GCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 SubstratesCoagulation factor X human
go.drugbank.com/drugs/DB13148ApprovedInvestigationalCoagulation Factor X (Human) solution is approved by the FDA for intravenous injection under the market name Coagadex which contains normally 100 IU/mL of coagulation Factor X derived from healthy donors … It is a two-chain glycoprotein with the molecular weight of approximately 59 kDa [A31472].
Mixtures: COFACT 250 IU/10 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET, COFACT 500 IU/20 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADETVorasidenib
go.drugbank.com/drugs/DB17097ApprovedInvestigational[A264209] It works by suppressing the levels of D-2-hydroxyglutarate (2-HG), an oncometabolite produced by mutant IDH1 and IDH2 isoforms. … Vorasidenib is a first-in-class dual isocitrate dehydrogenase-1 (IDH1) and isocitrate dehydrogenase-2 (IDH2) inhibitor.
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesAcepromazine
go.drugbank.com/drugs/DB01614InvestigationalVet approvedAcepromazine is one of the phenothiazine derivative psychotropic drugs, used little in humans, however frequently in animals as a sedative and antiemetic.
Synonyms: 10-(3-dimethylaminopropyl)phenothiazine-3-ethylone, 10-(3-dimethylaminopropyl)phenothiazin-3-yl methyl ketoneProducts: PLEGICIL 30 ML DAMLAHesperidin
go.drugbank.com/drugs/DB04703ApprovedInvestigationalHesperidin is a flavan-on glycoside found in citrus fruits.
Mixtures: NA, DIOKERN 450 MG/50 MG FILM KAPLI TABLET,30 ADETSargramostim
go.drugbank.com/drugs/DB00020ApprovedInvestigationalSargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. … Substitution of Leu23 leads to a difference from native protein.
Gamolenic acid
go.drugbank.com/drugs/DB13854ApprovedWithdrawnIt is converted to [DB00154], a biosynthetic precursor of monoenoic prostaglandins such as PGE1. … Gamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised of 18 carbon atoms with three double bonds [F27] that is most commonly found in human milk
Mixtures: Gla 130 Primrose Oil, Pro-gla CapsSynonyms: GLAPiperaquine
go.drugbank.com/drugs/DB13941ApprovedInvestigationalPiperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China . Its use declined in the 1980's as piperaquine resistant strains of Plasmodium falciparum appeared and artemisinin derivatives became availab...
Mixtures: EURARTESIM 320 MG/40 MG FILM COATED TABLETSCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inhibitors