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Susoctocog alfa
go.drugbank.com/drugs/DB11606ApprovedInvestigationalIt is the first recombinant porcine FVIII treatment approved for AHA that allows physicians to manage the treatment's efficacy and safety by measuring factor VIII activity levels in addition to clinical … Susoctocog alfa serves to temporarily restore the inhibited endogenous Factor VIII for effective hemostasis.
Celiprolol
go.drugbank.com/drugs/DB04846ApprovedInvestigationalWithdrawnCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris. … Celiprolol is not approved for use by the FDA in the treatment of vascular Ehlers–Danlos syndrome.
Indium In-111 chloride
go.drugbank.com/drugs/DB09490Approvedand for radiolabeling Zevalin (ibritumomab tiuxetan) in preparations used for radioimmunotherapy procedures. … Indium In-111 Chloride is a diagnostic radiopharmaceutical agent intended for radiolabeling OncoScint (satumomab pendetide) or ProstaScint (capromab pendetide) used for _in vivo_ diagnostic imaging procedures
Mixtures: OCTREOSCAN FOR INJECTION, Kit for the Preparation of Indium In 111 PentetreotidePeginesatide
go.drugbank.com/drugs/DB08894ApprovedWithdrawnChemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is not a replica of the structure itself. … Peginesatide is a synthetic peptide attached to polyethylene glycol for the treatment of anemia. The polyethylene glycol moiety helps make the drug less immunogenic and prolongs its plasma half-life.
Categories: Compounds used in a research, industrial, or household settingEstetrol
go.drugbank.com/drugs/DB12235ApprovedInvestigational[L33184] Estetrol (E4) is a native estrogen occurring naturally during pregnancy, but can be synthesized from a plant source and used for contraception. … [L33179] In Canada, Nextstellis was approved for use in March 2021; it was developed by Mithra and is marketed by Searchlight Pharma.[L33209]
Categories: Hormonal Contraceptives for Systemic UseZalcitabine
go.drugbank.com/drugs/DB00943ApprovedWithdrawnThis modification prevents the formation of 5' to 3' phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. … The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseTaurine
go.drugbank.com/drugs/DB01956ApprovedInvestigationalNutraceutical[A31396] This conditional amino acid can be either be manufactured by the body or obtained in the diet mainly by the consumption of fish and meat. … [L1058] The supplements containing taurine were FDA approved by 1984 and they are hypertonic injections composed by cristalline amino acids.[FDA label]
Mixtures: AMINOVEN SOLUTION FOR INFUSION 5%, SmofKabiven Emulsion for InfusionHydroxyprogesterone caproate
go.drugbank.com/drugs/DB06789ApprovedHydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. … In April 2023, the FDA withdrew its approval of Makena and its generics given an unfavorable risk-to-benefit assessment.[L46113]
Categories: Hormonal Contraceptives for Systemic UseCarbopol 974P
go.drugbank.com/drugs/DB05384ApprovedWithdrawnThe compound, known as BufferGel, was in advanced clinical trials for its ability to prevent pregnancy, but was discontinued. … It was under development by ReProtect LLC. It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies.
Categories: Compounds used in a research, industrial, or household settingAminobenzoic acid
go.drugbank.com/drugs/DB02362ApprovedWithdrawnIt used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Categories: Protectives Against UV-Radiation for Topical Use