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Displaying results 2141 - 2150 of 10000 in total
  1. Target

    Lipid A palmitoyltransferase PagP

    go.drugbank.com/bio_entities/BE0001965
    TargetEscherichia coli (strain K12)

    Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.

    Polypeptides: Lipid A palmitoyltransferase PagPSynonyms: Lipid A acylation protein
  2. Target

    Dihydroorotate dehydrogenase A (fumarate)

    go.drugbank.com/bio_entities/BE0002008
    TargetLactococcus lactis subsp. cremoris

    Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.

    Polypeptides: Dihydroorotate dehydrogenase A (fumarate)Synonyms: DHOD A
  3. Target

    Group A nerve fibers

    go.drugbank.com/bio_entities/BE0009708
    TargetRat

  4. Target

    BCL11 transcription factor A

    go.drugbank.com/bio_entities/BE0019545
    TargetHumans

    May function as a modulator of the transcriptional repression activity of NR2F2 (By similarity) … May play a role in hematopoiesis (By similarity). Essential factor in lymphopoiesis required for B-cell formation in fetal liver (By similarity).

    Polypeptides: BCL11 transcription factor A
  5. Drug

    Perampanel

    go.drugbank.com/drugs/DB08883
    ApprovedInvestigational

    Perampanel is a noncompetitive AMPA glutamate receptor antagonist. … It is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures.

    Synonyms: 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-oneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Inducers
  6. Drug

    Quinine

    go.drugbank.com/drugs/DB00468
    ApprovedInvestigational

    It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. … Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.

    Synonyms: GLS-1200, (R)-(6-methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanolMixtures: IRUDERM 1
  7. Drug

    Pimecrolimus

    go.drugbank.com/drugs/DB00337
    ApprovedInvestigational

    It is currently available as a topic cream used in the treatment of atopic dermatitis (eczema). … Pimecrolimus is an immunomodulating agent that was first marketed by Novartis under the trade name Elidel. It is now promoted in Canada by Galderma since early 2007.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Elidel 10 mg/g Creme, ELIDEL %1 KREM, 15 G
  8. Target

    Cholecystokinin receptor type A

    go.drugbank.com/bio_entities/BE0000402
    TargetHumans

    Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. … This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system

    Polypeptides: Cholecystokinin receptor type ASynonyms: CCK-A receptor
  9. Target

    Choline-phosphate cytidylyltransferase A

    go.drugbank.com/bio_entities/BE0000615
    EnzymeTargetHumans

    Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis

    Polypeptides: Choline-phosphate cytidylyltransferase ASynonyms: CT A, CCT A
  10. Target

    Catabolite control protein A

    go.drugbank.com/bio_entities/BE0001530
    TargetBacillus megaterium

    Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

    Polypeptides: Catabolite control protein A