Search
Amphetamine
go.drugbank.com/drugs/DB00182ApprovedIllicitInvestigationalAmphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. … This use derived into a large overproduction of amphetamine and all the surplus after the war finalized ended up in the black market, producing the initiation of the illicit abuse.[A18540]
Mixtures: Mixed Salts of a Single-Entity Amphetamine Product, Mixed Salts of a Single-Entity Amphetamine ProductCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesAripiprazole lauroxil
go.drugbank.com/drugs/DB14185ApprovedIt is a prodrug of [aripiprazole], which acts as a partial agonist at the D2 and 5-HT1A receptors, and as an antagonist at the 5-HT2A receptors [A34289]. … Affecting about 1% of the adult population in the United States and approximately 26 million people worldwide, schizophrenia is a chronic neurological disorder that may result in impairments in cognition
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesPrazosin
go.drugbank.com/drugs/DB00457ApprovedInvestigational[L5828] It belongs to the class of drugs known as alpha-1 antagonists. … Prazosin is a drug used to treat hypertension. Prazosin is marketed by _Pfizer_ and was initially approved by the FDA in 1988.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine, 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazolineEsterified estrogens
go.drugbank.com/drugs/DB09381ApprovedPreparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%. … Esterified estrogens contain a mixture of estrogenic substances; the principle component is estrone.
Mixtures: Eemt Hs, Covaryx HsCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesGlycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[L33110] It is one of the most commonly prescribed anticholinergic medications. … [L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium].
Mixtures: TRİMBOW 87/5/9 MCG AEROSOL İNHALASYON ÇÖZELTİSİ, 120 DOZ, TRYDONİS 87 MCG/5 MCG/9 MCG AEROSOL İNHALASYONU, ÇÖZELTİ, 120 DOZCategories: MATE 1 Substrates, Cytochrome P-450 SubstratesBalsalazide
go.drugbank.com/drugs/DB01014ApprovedThe chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenzoic acid. It is usually administered as the disodium salt. … Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK.
Categories: Non COX-2 selective NSAIDSSynonyms: (E)-5-({p-[(2-carboxyethyl)carbamoyl]phenyl}azo)-2-salicylic acid, (E)-5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoic acidChlorotrianisene
go.drugbank.com/drugs/DB00269ApprovedWithdrawnA powerful synthetic, non-steroidal estrogen. [PubChem]
Categories: Sex Hormones and Modulators of the Genital SystemEtanercept
go.drugbank.com/drugs/DB00005ApprovedInvestigationalIt is used to treat or manage a variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and juvenile idiopathic poly-articular arthritis (JIA). … [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1.
Products: BENEPALI 50MG ILO I E FER, ENBREL 25MG PUL+LSM GEF SPCarbimazole
go.drugbank.com/drugs/DB00389ApprovedCarbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.
Categories: Heterocyclic Compounds, 1-RingSynonyms: Ethyl 3-methyl-2-thioimidazoline-1-carboxylateLunsotogene parvec
go.drugbank.com/drugs/DB18278ApprovedInvestigationalIt is the first gene therapy to be approved under the Commissioner's National Priority Voucher (CNPV) pilot and represents one of the fastest BLA approvals in modern history, with a time between filing … [L56135,L56136] This landmark decision followed designations as a Regenerative Medicine Advanced Therapy (RMAT) and Fast Track, marking the first-ever gene therapy approved to restore a neurosensory function