Search
Clofarabine
go.drugbank.com/drugs/DB00631ApprovedInvestigationalClofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. … Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed.
Categories: OCT2 Substrates with a Narrow Therapeutic Index, OAT3/SLC22A8 Substrates with a Narrow Therapeutic IndexSynonyms: Cl-F-Ara-APentazocine
go.drugbank.com/drugs/DB00652ApprovedVet approvedIt is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Products: Pentazocine-Fresenius 30 mg/ml injection, Talwin - Liq 30mg/mlBenzatropine
go.drugbank.com/drugs/DB00245ApprovedInvestigationalpotency for dopamine uptake inhibition as well as a decreased inhibition of serotonin and norepinephrine. … Benztropine, with the chemical formula 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor used for the symptomatic treatment of Parkinson's disease.
Categories: Ethers of Tropine or Tropine DerivativesProducts: TICOLIN 2 MG/2 ML IM/IV ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL,1 ADET, BENZATROPINE PHEBRA SOLUTION FOR INJECTION 2 MG/2 MLPitavastatin
go.drugbank.com/drugs/DB08860ApprovedInvestigational[A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … [A181397, A181403] While all statin medications are considered equally effective from a clinical standpoint, [rosuvastatin] is considered the most potent; doses of 10 to 40mg [rosuvastatin] per day
Categories: Hypolipidemic Agents Indicated for HyperlipidemiaProducts: Trolise 1 mg Filmtabletten, PITAMIN 1 MG EFERVESAN TABLET, 30 ADETEpcoritamab
go.drugbank.com/drugs/DB16672ApprovedInvestigationalAlthough this regimen is effective in up to 60% of patients, patients with relapsed or refractory DLBCL have poor outcomes. … [L46516] It is administered subcutaneously and is currently being evaluated as a monotherapy and in combination for the treatment of a variety of hematologic malignancies.
Products: Tepkinly 4 mg/0,8 ml Enjeksiyonluk Çözelti (1 adet), Tepkinly 48 mg Enjeksiyonluk Çözelti (1 adet)Coal tar
go.drugbank.com/drugs/DB11082ApprovedCoal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. … It has been indicated for local relief of itching, dryness, and irritation caused by psoriasis, seborrhea and eczema.
Mixtures: Multi-action Denorex 2-IN-1 Dandruff Shampoo + Conditioner, Targel SaProducts: Jamp-coal Tar 10%, COAL TAR SOLUTION 10% IN AQUEOUS CREAMSilodosin
go.drugbank.com/drugs/DB06207ApprovedInvestigationalneck, prostate, and prostatic urethra: the α<sub>1A</sub> subtype accounts for approximately 75% of α1-adrenoceptors in the prostate. … Silodosin is a selective antagonist of alpha(α)-1 adrenergic receptors that binds to the α<sub>1A</sub> subtype with the highest affinity. α1-adrenergic receptors regulate smooth muscle tone in the bladder
Categories: Peripheral alpha-1 blockers, Adrenergic alpha-1 Receptor AntagonistsProducts: SILODOSIN AL 4 MG HKP, SILODOSIN AL 8 MG HKPSofosbuvir
go.drugbank.com/drugs/DB08934ApprovedInvestigationalWith the price per pill set at $1000, a 12-week treatment can cost upwards of $84,000 per patient [A19636]. … the intent to cure, or achieve a sustained virologic response (SVR), after 12 weeks of daily therapy.
Mixtures: VOSEVİ 400 MG/ 100 MG/ 100 MG FİLM KAPLI TABLET, 28 ADET, HARVONI 90 MG/400 MG FILM KAPLI TABLET, 84 ADETCategories: Heterocyclic Compounds, 1-Ring, Antivirals for Systemic UsePolymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line[A176429]. … Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label].
Mixtures: HEKSA 30 MG/G + 10000 I.U./G MERHEM, 10 Person ANSICategories: Pore Forming Cytotoxic Proteins, Antibacterials for Systemic UseDimercaprol
go.drugbank.com/drugs/DB06782ApprovedIn addition, it has in the past been used for the treatment of Wilson's disease, a genetic disorder in which the body tends to retain copper. … Dimercaprol has toxic potential, and its use may be followed by a variety of adverse effects.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 2,3-dimercapto-1-propanol, 2,3-mercaptopropan-1-ol