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Ospemifene
go.drugbank.com/drugs/DB04938ApprovedOspemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause … FDA approved on February 26, 2013.
Ethylhexyl methoxycrylene
go.drugbank.com/drugs/DB11226ApprovedIt is used as a solvent for crystalline UV filters and is easily emulsified and suitable for use in various lotions, creams, sprays, sticks, and gel formulations [F104]. … It currently enjoys regional approvals in Canada, the EU, and the US [L2847].
Tolbutamide
go.drugbank.com/drugs/DB01124ApprovedTolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). … Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor.
Synonyms: N-n-Butyl-N'-tosylurea, N-(Sulfonyl-p-methylbenzene)-N'-N-butylureaCategories: Tests for Diabetes, Drugs Used in DiabetesDoxycycline
go.drugbank.com/drugs/DB00254ApprovedInvestigationalVet approvedDoxycycline is a broad-spectrum antibiotic synthetically derived from [oxytetracycline].[L42880] It is a second-generation tetracycline that was first discovered in 1967. … [A174034] Doxycycline is used to treat a wide variety of gram-positive and gram-negative bacterial infections. It is also used to treat acne and malaria.[A251730]
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Doxycycline for Injection USP, DOXYCYCLIN AL 100Avelumab
go.drugbank.com/drugs/DB11945ApprovedInvestigationalIt is used in the treatment of Merkel cell carcinoma, metastatic urothelial carcinoma, or renal cell carcinoma. … Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: BAVENCIO CONCENTRATE FOR SOLUTION FOR INFUSION 200MG/10ML, BAVENCIO 200 mg/10mL concentrate for solution for infusionVibrio cholerae CVD 103-HgR strain live antigen
go.drugbank.com/drugs/DB14443ApprovedInvestigational_Vibrio cholerae_ CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization against _Vibrio cholerae_ serogroup O1. … [A244494] Cholera outbreaks remain a major global public health problem that mainly affects countries with limited access to clean water, poor hygiene, and proper sanitation; thus, effective vaccines to
Amlexanox
go.drugbank.com/drugs/DB01025ApprovedWithdrawnAmlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. … Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers.
Categories: Drugs for Obstructive Airway DiseasesInternational brands: OraDisc AOrforglipron
go.drugbank.com/drugs/DB18964ApprovedInvestigationalOrforglipron is a first-in-class oral, non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist. … [L56123] On April 1, 2026, the US FDA granted approval to orforglipron for use alongside diet and exercise to aid in weight reduction in certain patient populations.
CX-052075
go.drugbank.com/drugs/DB31655Approveda more targeted immune response and the use of a significantly smaller amount of mRNA per dose. … [L53413,A274083] mNEXSPIKE was approved by the US FDA in June 2025 for use in patients who have been previously vaccinated with any COVID-19 vaccine and who are at a higher risk of severe outcomes from
Isatuximab
go.drugbank.com/drugs/DB14811ApprovedInvestigationalgranted Orphan Drug designation and approved on March 2nd, 2020, for the treatment of multiple myeloma. … [L12099] It is a cytolytic antibody targeted against CD38, a glycoprotein found on the surface of some immune cells that is highly expressed by malignant plasma cells in multiple myeloma.