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Chlorobutanol
go.drugbank.com/drugs/DB11386ApprovedVet approvedWithdrawnDue to the long terminal half-life of 37 days, the use of chlorobutanol as a sedative is limited because of the considerable accumulation which will occur following multiple dosing [A32743]. … As a long-term stabilizer of multi-ingredient preparations, chlorobutanol is normally used at a concentration of 0.5%. At this concentration, it also conserves its antimicrobial activity.
Categories: Compounds used in a research, industrial, or household settingMetamfetamine
go.drugbank.com/drugs/DB01577ApprovedIllicitInvestigationalWithdrawnIt is a scheduled drug in most countries due to its high potential for addiction and abuse. … Metamfetamine (methamphetamine) is a psychostimulant and sympathomimetic drug, and a member of the amphetamine group of sympathomimetic amines.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesSynonyms: d-deoxyephedrine, d-desoxyephedrineLimaprost
go.drugbank.com/drugs/DB09211InvestigationalOno and DSP also discontinued the development of limaprost alfadex for the additional indication of cervical spondylosis in 2008 due to the failure to demonstrate the anticipated efficacy in a Phase II … Limaprost (as Limaprost alfadex; CAS number 88852-12-4) is an oral prostaglandin E1 analog.
Bromopride
go.drugbank.com/drugs/DB09018InvestigationalBromopride is a dopamine antagonist used as an antiemetic. Its prokinetic properties are similar to those of metoclopramide. It is unavailable in America or the United Kingdom.
Categories: Dopamine D2 Receptor AntagonistsApalutamide
go.drugbank.com/drugs/DB11901ApprovedInvestigationalHigher prostate-specific antigen (PSA) and shorter PSA doubling time (PSA DT) are associated with a higher risk for metastases and death [A31846]. … Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements [A31846]
Oxogluric acid
go.drugbank.com/drugs/DB08845InvestigationalNutraceuticaland reduces nitrogen by combining with it as well. … Oxogluric acid is sold as a dietary supplement to athletes to improve their performance by helping to remove excess ammonia, but it is not officially approved for this indication and only experimental
Midodrine
go.drugbank.com/drugs/DB00211ApprovedInvestigationalAn ethanolamine derivative that is an adrenergic alpha agonist. It is used as a vasoconstrictor agent in the treatment of hypotension.
Synonyms: DL-N1-(beta-Hydroxy-2,5-dimethoxyphenethyl)glycinamidAutologous cultured chondrocytes
go.drugbank.com/drugs/DB10997ApprovedInvestigationalAutologous cultured chrondrocytes are used as autologous cell therapy to repair articular cartilage injuries in the knee (femoral condyle) due to acute or repetitive trauma. … It serves as an alternative repair treatment for patients with inadequate response to pre-existing surgical methods.
Thymol
go.drugbank.com/drugs/DB02513ApprovedInvestigationalA phenol obtained from thyme oil or other volatile oils. It is used as a stabilizer in pharmaceutic preparations. … It has been used for its antiseptic, antibacterial, and antifungal actions, and was formerly used as a vermifuge. (Dorland, 28th ed)
Mixtures: Buenos Dias de Personna mint, Buenos Dias de Personna originalReslizumab
go.drugbank.com/drugs/DB06602ApprovedInvestigationalCinqair is indicated as an add-on maintenance therapy for adults with severe asthma with an eosinophilic phenotype. … In addition, a significant improvement in lung function was seen, as measured by the volume of air exhaled by patients in one second [L1133].