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Vilanterol
go.drugbank.com/drugs/DB09082ApprovedInvestigational[A259961] Vilanterol is 1000 and 400 fold more selective for β2 than β1 and β3 adrenoceptors, respectively, with a faster onset of action than salmeterol. … with the (R)-configuration.
Mixtures: RELVAR ELLIPTA 100/25 MCG KULLANIMA HAZIR INHALASYON TOZU ,3 X 30, ANORO ELLIPTA 62.5 MCG + 25 MCG KULLANIMA HAZIR INHALASYON TOZU, 3 X 30 DOZCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEstradiol acetate
go.drugbank.com/drugs/DB13952ApprovedVet approvedThe primary source of estrogen in normally cycling adult women is the ovarian follicle, which secretes 70 to 500 mcg of estradiol daily, depending on the phase of the menstrual cycle. … As a pro-drug of estradiol, estradiol acetate therefore has the same downstream effects within the body through binding to the Estrogen Receptor (ER) including ERα and ERβ subtypes, which are located in
Categories: Cytochrome P-450 CYP1A1 Substrates, Cytochrome P-450 SubstratesSynonyms: Estradiol 3-acetate, Estradiol-3-acetateDioxybenzone
go.drugbank.com/drugs/DB11221ApprovedWithdrawnDioxybenzone, or benzophenone-8, is an organic compound derived from [DB01878] that is used as a sunscreen agent. It absorbed UV-B and UV-AII rays. … Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3% [L2525].
Synonyms: 2,2'-Dihydroxy-4-methoxybenzophenonePiretanide
go.drugbank.com/drugs/DB02925ApprovedPiretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in
Mixtures: RAMITANID AL 5MG/6MG, RAMIPRIL HEXAL PL PIR5/6MGCategories: Genito Urinary System and Sex HormonesIndobufen
go.drugbank.com/drugs/DB12545InvestigationalIndobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 2-RingProducts: INDOBUFENE EGIbudilast
go.drugbank.com/drugs/DB05266InvestigationalIbudilast is an anti-inflammatory and neuroprotective oral agent which shows an excellent safety profile at 60 mg/day and provides significantly prolonged time-to-first relapse and attenuated brain volume … (codes: AV-411 or MN-166), but is approved for use as an antiinflammatory in Japan.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingMipomersen
go.drugbank.com/drugs/DB05528ApprovedMipomersen sodium prevents the formation of apo B-100, resulting in a decrease in the levels of apolipoprotein B (apo B), low density lipoprotein (LDL), and total cholesterol. … Mipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic phosphorothioate oligonucleotide.
Categories: Apolipoprotein B-100 Synthesis Inhibitor, Compounds used in a research, industrial, or household settingFruquintinib
go.drugbank.com/drugs/DB11679ApprovedInvestigationalFruquintinib is a novel small-molecule anti-VEGFR that targets VEGFR-1,-2, and -3 to inhibit angiogenesis. … The first approach can be exemplified by [bevacizumab], a VEGF-A trap antibody.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesEstetrol
go.drugbank.com/drugs/DB12235ApprovedInvestigationalEstetrol is the first new estrogen introduced to the USA in over 50 years and is the first approved estetrol product in the world. … [L33184] Estetrol (E4) is a native estrogen occurring naturally during pregnancy, but can be synthesized from a plant source and used for contraception.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesHesperidin
go.drugbank.com/drugs/DB04703ApprovedInvestigationalHesperidin is a flavan-on glycoside found in citrus fruits.
Mixtures: DIOKERN 450 MG/50 MG FILM KAPLI TABLET,30 ADET, DIOKERN 450 MG/50 MG FILM KAPLI TABLET,60 ADETCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring