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Displaying results 211 - 220 of 2507 in total
  1. Indication

    Neuroendocrine Tumors

    go.drugbank.com/conditions/DBCOND0029892
    Drugs: Etoposide
    Synonyms: Neuroendocrine Tumor (NET), Neuroendocrine Tumors (NET)
  2. Drug

    Fentanyl

    go.drugbank.com/drugs/DB00813
    ApprovedIllicitInvestigationalVet approved

    Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L66...

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: FENTANYL-PF 100 MCG/2 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 10 ADET, FENTANYL-PF 500 MCG/10 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET
  3. Drug

    Asciminib

    go.drugbank.com/drugs/DB12597
    ApprovedInvestigational

    Asciminib is a tyrosine kinase inhibitor (TKI) used in the treatment of chronic-phase Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). … [L39005] It has also shown benefit in Ph+ CML with the T315I mutation, which produces a mutant BCR-ABL1 which is typically treatment-resistant as compared to wild-type BCR-ABL1.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  4. Drug

    Chlorhexidine

    go.drugbank.com/drugs/DB00878
    ApprovedInvestigationalVet approvedWithdrawn

    Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous memb...

    Synonyms: 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide)Products: Dermsafe Pc, (LAVADO ANTISEPTICO DE MANOS Y CUERPO CON GLUCONATO DE CLORHEXIDINA AL 2% P/P FRASCO
  5. Drug

    Raxibacumab

    go.drugbank.com/drugs/DB08902
    ApprovedInvestigational

    Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons.

    Synonyms: PA mAb
  6. Drug

    TBC-3711

    go.drugbank.com/drugs/DB05407
    Investigational

    TBC3711 is a next-generation endothelin antagonist that is being studied through oral and intravenous formulations by Encysive Pharmaceuticals.

  7. Drug

    Ospemifene

    go.drugbank.com/drugs/DB04938
    Approved

    Ospemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.

    Synonyms: 2-(p-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  8. Drug

    Benzalkonium

    go.drugbank.com/drugs/DB11105
    ApprovedInvestigational

    Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride [FDA...

    Mixtures: PM Toothache Relief, Orajel Instant Pain Relief Severe PMProducts: NEXT Antibacterial Bar, Next 1 Anti-bacterial Deodorant
  9. Drug

    XEN-2174

    go.drugbank.com/drugs/DB05012
    Experimental

    NET is the primary mechanism regulating the biological effects of norepinephrine (NE) on the body. … XEN-2174 represents a new class of molecules, called the chi conopeptides that selectively inhibit the Norepinephrine Transporter (NET).

  10. Drug

    Morphine

    go.drugbank.com/drugs/DB00295
    ApprovedInvestigational

    Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though th...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Astramorph PF