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Displaying results 211 - 220 of 6073 in total
  1. Drug

    Busulfan

    go.drugbank.com/drugs/DB01008
    ApprovedInvestigational

    Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. It has been used in the palliative treatment of chronic myeloid leukemia (my...

    Products: Busulfan Kabi Injection 6mg/ml Concentrate for Solution for Infusion, Busulfan for Injection
  2. Drug

    Obinutuzumab

    go.drugbank.com/drugs/DB08935
    ApprovedInvestigational

    This chemical modification significantly enhances its affinity for FcγRIII receptors on immune effector cells.

    Products: GAZYVA 1000 MG/ 40 ML CONCENTRATE FOR SOLUTION FOR INFUSION, GAZYVA CONCENTRATE FOR SOLUTION FOR INFUSION 1000MG/40ML
  3. Drug

    Eugenol

    go.drugbank.com/drugs/DB09086
    ApprovedInvestigational

    There are a number of unapproved OTC products available containing eugenol that advertise its use for the treatment of toothache. … It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control.

    Products: Orajel Naturals FAst Relief for Teething Pain, Baby Orajel Naturals Remedy for Teething Pain Relief
  4. Drug

    Betaine

    go.drugbank.com/drugs/DB06756
    ApprovedInvestigationalNutraceutical

    The FDA and EMA have approved the product Cystadane (betaine anhydrous, oral solution) for the treatment of homocystinuria,[L43105,L43115] and the EMA has approved the use of Amversio (betaine anhydrous

    Products: Betaine Anhydrous For Oral Solution, Betaine Anhydrous for Oral Solution
  5. Drug

    Eribulin

    go.drugbank.com/drugs/DB08871
    ApprovedInvestigational

    Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic … Eribulin is also being investigated for use in the treatment of advanced solid tumors [A7439].

    Products: Halaven Solution for Injection 0.5mg/mL, HALAVEN 0.5 mg/ml solution for injection
  6. Drug

    Polymyxin B

    go.drugbank.com/drugs/DB00781
    ApprovedInvestigationalVet approved

    Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. … It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of _Pseudomonas aeruginosa_[FDA Label].

    Mixtures: Polysporin for Kids, Polysporin for StitchesCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  7. Drug

    Olodaterol

    go.drugbank.com/drugs/DB09080
    ApprovedInvestigational

    Despite similarities in symptoms, olodaterol is not indicated for the treatment of acute exacerbations of COPD or for the treatment of asthma. … Single doses of olodaterol have been shown to improve forced expiratory volume in 1 sec (FEV1) for 24 h in patients with COPD, allowing once daily dosing.

    Categories: Drugs for Obstructive Airway DiseasesProducts: Striverdi Respimat Solution for Inhalation 2.5 microgram/ actuation, SPIOLTO® RESPIMAT® RE-USABLE SOLUTION FOR INHALATION 2.5 MICROGRAM / 2.5 MICROGRAM
  8. Drug

    Tremelimumab

    go.drugbank.com/drugs/DB11771
    ApprovedInvestigational

    [A253717, A253722] After receiving an EMA Committee for Medicinal Products for Human Use (CHMP) recommendation in December 2022, tremelimumab was approved for combined use with [durvalumab].[L46188] … CTLA-4 is a cell surface receptor expressed on activated T cells to act as a negative regulator for T cells.

    Products: Imjudo Concentrate for Solution for Intravenous Infusion 20 mg/mL
  9. Drug

    Urofollitropin

    go.drugbank.com/drugs/DB00094
    ApprovedVet approvedWithdrawn

    Urofollitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use in gamete intrafallopian transfer (GIFT) or in vitro fertilization (IVF).

    Products: BRAVELLE POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 75 IU, Fostimon 75 IU powder and solvent for solution for injection
  10. Drug

    Choriogonadotropin alfa

    go.drugbank.com/drugs/DB00097
    ApprovedInvestigational

    Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-1...

    Products: Ovidrel Solution for Injection 250 mcg, OVIDREL 250MCG/0.5ML SOLUTION FOR INJECTION