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Methantheline
go.drugbank.com/drugs/DB00940ApprovedMethantheline is a synthetic antispasmodic. Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. … (reflex neurogenic bladder in children).
Categories: Drugs for Functional Gastrointestinal DisordersAmphotericin B
go.drugbank.com/drugs/DB00681ApprovedInvestigationalAmphotericin B shows a high order of in vitro activity against many species of fungi. … The antibiotic is without effect on bacteria, rickettsiae, and viruses.
Categories: Compounds used in a research, industrial, or household setting, Antimycotics for Systemic UseProducts: L- AMPHOSEVEN 50, AMPHOTRET FOR INJECTION USP 50MGAmlexanox
go.drugbank.com/drugs/DB01025ApprovedWithdrawnAmlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. … Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers.
Categories: Drugs for Obstructive Airway DiseasesInternational brands: OraDisc AFludrocortisone
go.drugbank.com/drugs/DB00687ApprovedInvestigationalFludrocortisone is a synthetic mineralocorticoid used in conjunction with [hydrocortisone] to replace missing endogenous corticosteroids in patients with adrenal insufficiency. … [A187169,A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9-position
Categories: Corticosteroids for Systemic Use, Corticosteroids for Systemic Use, PlainIdecabtagene vicleucel
go.drugbank.com/drugs/DB16665ApprovedInvestigational[A232563] Multiple myeloma is typically treated with an immunomodulatory agent like [lenalidomide],[A232593] a proteasome inhibitor like [bortezomib], or an anti-CD38 monoclonal antibody like [isatuximab … [A232558,A232563,L32858] These therapies involve extracting and genetically manipulating T-cells from a patient to express a CAR for a tumor specific antigen.
Mirikizumab
go.drugbank.com/drugs/DB14910ApprovedInvestigational[L46237,L46257] Mirikizumab is approved in Japan[L46252] and received a positive opinion from the EMA's Committee for Medicinal Products for Human Use in March 2023. … It inhibits the actions of interleukin-23 (IL-23), a pro-inflammatory cytokine that activates pathways contributing to the development of inflammatory diseases.
Vibrio cholerae CVD 103-HgR strain live antigen
go.drugbank.com/drugs/DB14443ApprovedInvestigational_Vibrio cholerae_ CVD 103-HgR strain live antigen is a component of Vaxchora, an oral vaccine for immunization against _Vibrio cholerae_ serogroup O1. … [A244494] Cholera outbreaks remain a major global public health problem that mainly affects countries with limited access to clean water, poor hygiene, and proper sanitation; thus, effective vaccines to
Nedaplatin
go.drugbank.com/drugs/DB13145ApprovedInvestigationalNedaplatin is a second generation platinum analog [A20300]. It is less nephrotoxic than [DB00515] but has proven equally effective. It was approved for use in Japan in 1995.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexIopromide
go.drugbank.com/drugs/DB09156ApprovedIopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. … favorable safety profile, with only 0.7% of patients in a 2 years study experiencing adverse events.
Categories: Compounds used in a research, industrial, or household settingSynonyms: N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methylisophthalamideDelgocitinib
go.drugbank.com/drugs/DB16133ApprovedInvestigationalDelgocitinib is a pan-Janus kinase (JAK) inhibitor. After the first global approval in Japan,[A264693] delgocitinib was also approved by the European Commission on September 23, 2024. … [L51913] It works to reduce the inflammatory response in inflammatory skin disorders.[A264703] On July 23, 2025, delgocitinib was also granted approval by the FDA.[L53508]
Categories: Agents for Dermatitis, Excluding Corticosteroids