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Alirocumab
go.drugbank.com/drugs/DB09302ApprovedInvestigationalAlirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of … PCSK9 inhibition facilitates more LDL-C clearance from the blood.
Categories: Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) InhibitorsProducts: PRALUENT®150MG/ML SOLUCIÓN INYECTABLE, PRALUENT® 75MG/ML SOLUCIÓN INYECTABLEDiamorphine
go.drugbank.com/drugs/DB01452ApprovedIllicitDiamorphine (heroin) is a narcotic analgesic that may be habit-forming. It is a controlled substance (opium derivative) listed in the U.S. … However, under the name diamorphine, heroin is a legal prescription drug in the United Kingdom.
Categories: Heterocyclic Compounds with 4 or More RingsSynonyms: O,O'-DiacetylmorphineiCo-007
go.drugbank.com/drugs/DB05268Investigational) such as age-related macular degeneration (AMD) and diabetic retinopathy(DR). … iCo-007 (formerly known as ISIS 13650) is a second generation antisense compound being developed by iCo for the treatment of various eye diseases caused by the formation of new blood vessels (angiogenesis
Turpentine
go.drugbank.com/drugs/DB11120ApprovedIt is used as a solvent and base material in organic synthesis reactions. … Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted from live trees, mainly pine, through distillation of resin.
Mixtures: Chan Yat Hing She Kun Wool Lok Medicated Oil, NORAVER UCategories: Compounds used in a research, industrial, or household settingQuizartinib
go.drugbank.com/drugs/DB12874ApprovedInvestigationalQuizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated … maintenance monotherapy resulted in a 22% reduction in the risk of death.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: N-(5-(1,1-Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1-b)benzothiazol-2-yl)phenyl)ureaLevosalbutamol
go.drugbank.com/drugs/DB13139ApprovedThe enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has adverse effects have led to the development of an enantiomerically pure (R)-salbutamol formulation known as levosalbutamol … [Salbutamol] has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer.
Categories: Adrenergic beta-2 Receptor Agonists, Cytochrome P-450 CYP3A InhibitorsSynonyms: R-salbutamol, (R)-salbutamolEstrone sulfate
go.drugbank.com/drugs/DB04574ApprovedEstrone sulfate (as estropipate) is a form of estrogen. … types of infertility, treatment of some conditions leading to underdevelopment of female sexual characteristics, treatment of vaginal atrophy, treatment of some types of breast cancer (particularly in men
Synonyms: Estrone 3-sulfate, Estrone-3-sulphateCategories: MATE 1 Substrates, MATE 2 SubstratesHalofantrine
go.drugbank.com/drugs/DB01218ApprovedWithdrawnHalofantrine is an antimalarial. It belongs to the phenanthrene class of compounds that includes quinine and lumefantrine.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesAtl146e
go.drugbank.com/drugs/DB05191InvestigationalATL146e is an anti-inflammatory compounds which is an agonist of A2A adenosine receptors.
Categories: Adenosine A receptor agonists, Heterocyclic Compounds, 2-RingSodium hydroxide
go.drugbank.com/drugs/DB11151ApprovedThe use of this compound has been shown to effectively reduce prion levels in an in vitro inactivation assay [A32334]. … Interestingly, sodium hydroxide has been studied for its use in the treatment of prion disease (as occurs in mad cow disease and kuru).
Mixtures: AMINOPLASMAL® 10% E, AMINOPLASMAL® 10% ECategories: Compounds used in a research, industrial, or household setting