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HMI-103
go.drugbank.com/drugs/DB17684InvestigationalHMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.
Hydroxypropyl cellulose
go.drugbank.com/drugs/DB00840ApprovedHydroxypropyl cellulose is an ether of cellulose where some of the hydroxyl groups of the cellulose have been hydroxypropylated forming -OCH2CH(OH)CH3 groups. … As a food additive, hydroxypropyl cellulose is used as a thickener and as an emulsion stabilizer.
Synonyms: Cellulose, 2-hydroxypropyl ether, Hydroxypropyl cellulose (type H)International brands: A-GelCurcuma aromatica root oil
go.drugbank.com/drugs/DB11301ApprovedThe wild ginger has been used as a cosmetic herbal where its rhizomes exhibit a distinct fragrance and color. … The major constituents of Curcuma aromatica root oil are reported to be camphor, curzerenone, α-turmerone, ar-turmerone and 1,8-cineole [A27219].
Ferritin heavy chain
go.drugbank.com/bio_entities/BE0000399TargetCarrierHumansDelivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron (PubMed:24695223, PubMed:26436293)
Synonyms: Cell proliferation-inducing gene 15 proteinAspartate--tRNA ligase, cytoplasmic
go.drugbank.com/bio_entities/BE0000725TargetHumansCatalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA
Synonyms: Cell proliferation-inducing gene 40 proteinActin, aortic smooth muscle
go.drugbank.com/bio_entities/BE0005076TargetHumansActins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells
Synonyms: Cell growth-inhibiting gene 46 proteinBoldenone
go.drugbank.com/drugs/DB01541ExperimentalIllicitVet approvedBoldenone is an anabolic steroid developed for veterinary use, mostly for treatment of horses. It is not indicated for use in humans in the US and is only available through veterinary clinics.
Synonyms: 1,4-Androstadien-17β-ol-3-one, 1,4-Androstadien-17beta-ol-3-oneRabies immune globulin, human
go.drugbank.com/drugs/DB11603ApprovedPersons previously vaccinated with other types of rabies vaccines in whom adequate antibody levels have not been demonstrated should receive full post-exposure prophylaxis with RIG and a cell culture-produced … IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced
Products: Hyperrab S/d, BERIRAB(R) PGeraniol
go.drugbank.com/drugs/DB14183ApprovedInterestingly, geraniol has also been shown to sensitize tumour cells to commonly used chemotherapies including [DB00544] and [DB01248] and represents a promising cancer chemopreventive agent [A34263]. … Due to its anticancer effects, geraniol has been found to be effective against a broad range of cancers including breast, lung, colon, prostate, pancreatic, skin, liver, kidney and oral cancers [A34262
Synonyms: (E)-3,7-Dimethyl-2,6-octadien-1-ol, 2-trans-3,7-Dimethyl-2,6-octadien-1-olGefapixant
go.drugbank.com/drugs/DB15097ApprovedIt has been estimated that 5-10% of adults globally suffer from chronic cough, which is defined as a cough lasting longer than eight weeks. … [L48596] Gefapixant is a novel antagonist of the P2X3 receptor that works to reduce the cough reflex in patients with chronic cough.
Categories: MATE 1 Substrates, MATE 2 Substrates