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Finerenone
go.drugbank.com/drugs/DB16165ApprovedInvestigational[A236544] More selective nonsteroidal mineralocorticoid antagonists such as [apararenone], [esaxerenone], and finerenone were later developed.
Sulfacetamide
go.drugbank.com/drugs/DB00634ApprovedAn anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Mixtures: Metimyd Oph SusCycloserine
go.drugbank.com/drugs/DB00260ApprovedInvestigationalAntibiotic substance produced by Streptomyces garyphalus.
Iodide I-131
go.drugbank.com/drugs/DB09293ApprovedInvestigationalLow levels of beta radiation are also known for causing cancer as this dose is highly mutagenic. … Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy.
Aceclofenac
go.drugbank.com/drugs/DB06736ApprovedAceclofenac belongs to BCS Class II as it possesses poor aqueous solubility [A19667]. … Aceclofenac is also reported to be effective in other painful conditions such as dental and gynaecological conditions [A19672].
Asciminib
go.drugbank.com/drugs/DB12597ApprovedInvestigational[A241065] Asciminib is unique in that it acts as an allosteric inhibitor, binding at the myristoyl pocket of the BCR-ABL1 protein and locking it into an inactive conformation. … More specifically, it is an inhibitor of the ABL1 kinase activity of the BCR-ABL1 fusion protein[L38995] which serves as a driver of CML proliferation in most patients with the disease.
QR-334
go.drugbank.com/drugs/DB05473ExperimentalThe symptom is associated with many diseases including Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s Disease, Cerebral Palsy, Parkinson's Disease, and Muscular Dystrophy.
Diloxanide
go.drugbank.com/drugs/DB08792ExperimentalDiloxanide (as [Diloxanide furoate]) is an anti-protozoal drug used in the treatment of Entamoeba histolytica and some other protozoal infections.
Toluene
go.drugbank.com/drugs/DB11558InvestigationalVet approvedIt is a mono-substituted benzene derivative used in veterinary medicine as a treatment for various parasites in dogs and cats.
Mafenide
go.drugbank.com/drugs/DB06795ApprovedVet approvedWithdrawnMafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns. In 1998, mafenide acetate was approved under the F...