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Sotrovimab
go.drugbank.com/drugs/DB16355ApprovedInvestigational[L34425, L34430, L34440] However, in April 2022, the FDA removed the EUA for sotrovimab due to the rising COVID-19 cases caused by the Omicron BA.2 sub-variant, where the drug is ineffective. … [L34440] Sotrovimab was initially been granted emergency use authorization (EUA) to treat mild-to-moderate COVID-19 on May 26, 2021, based on interim results from a clinical trial, where sotrovimab was
Lutetium Lu 177 dotatate
go.drugbank.com/drugs/DB13985ApprovedInvestigationalLutetium Lu 177 dotatate was approved by the FDA as Lutathera in January 2018 for intravenous injection. … Lutetium Lu 177 dotatate may also be referred to as 177Lu-DOTA-Tyr3-octreotate.
Iloperidone
go.drugbank.com/drugs/DB04946ApprovedInvestigationalIloperidone is a benzisoxazole [A263557] and an atypical antipsychotic agent that was first approved by the FDA on May 6, 2009.
Prednisolone phosphate
go.drugbank.com/drugs/DB14631ApprovedInvestigationalVet approved[A187463] Prednisolone phosphate was granted FDA Approval on 19 December 1973.[L14144]
Cholic Acid
go.drugbank.com/drugs/DB02659ApprovedInvestigationalenzyme defects, and for peroxisomal disorders (such as Zellweger syndrome). … [PubChem] Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid synthesis disorders due to single
Chloramphenicol succinate
go.drugbank.com/drugs/DB07565Approved[L14174] Chloramphenicol succinate was granted FDA approval on 20 February 1959.[L12711] … [A204065] Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias.
Guanidine
go.drugbank.com/drugs/DB00536ApprovedA strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. … It is also used in laboratory research as a protein denaturant.
Promazine
go.drugbank.com/drugs/DB00420ApprovedVet approvedWithdrawnIt is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States.
Epofolate
go.drugbank.com/drugs/DB12266InvestigationalAntitumor activity was not demonstrated and further development of BMS-753493 has been discontinued. … Epofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to selectively target folate receptor expressing cancer cells.
Danicopan
go.drugbank.com/drugs/DB15401ApprovedInvestigational[A263506] It was subsequently approved by the FDA in March 2024.[L50386] … [L50381] It was first approved in January 2024 in Japan for patients with PNH,[A263506,L50416] shortly after which the EMA adopted a positive opinion and recommended granting it marketing authorization