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Nedocromil
go.drugbank.com/drugs/DB00716ApprovedA pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with asthma, including eosinophils, neutrophils, macrophages, mast cells, monocytes, and platelets.
Eplontersen
go.drugbank.com/drugs/DB16199ApprovedInvestigationalmultiple organs, although wild-type misfolded TTR has also been observed to contribute to the disease pathophysiology. … [A262985] As eplontersen targets both the WT and mutant TTR, it poses tremendous promises as a treatment.
Autologous cultured chondrocytes
go.drugbank.com/drugs/DB10997ApprovedInvestigationalAutologous cultured chrondrocytes are used as autologous cell therapy to repair articular cartilage injuries in the knee (femoral condyle) due to acute or repetitive trauma. … It serves as an alternative repair treatment for patients with inadequate response to pre-existing surgical methods.
Terpin hydrate
go.drugbank.com/drugs/DB13163ApprovedWithdrawnElixirs of terpin hydrate are still available to patients as prescription medications to be prepared by specialty compounding pharmacies. … Terpin hydrate is an expectorant, commonly used to loosen mucus and ease congestion in patients presenting with acute or chronic bronchitis, and related pulmonary conditions.
Fluvoxamine
go.drugbank.com/drugs/DB00176ApprovedInvestigationalThough it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeAsenapine
go.drugbank.com/drugs/DB06216ApprovedInvestigationalAsenapine also belongs to the dibenzo-oxepino pyrrole class. It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeChloroxine
go.drugbank.com/drugs/DB01243ApprovedWithdrawnChloroxine is a synthetic antibacterial compound. Chloroxine is a compound used in some shampoos for the treatment of dandruff and seborrheic dermatitis of the scalp.
Choline magnesium trisalicylate
go.drugbank.com/drugs/DB01401ApprovedCholine magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the f...
Palivizumab
go.drugbank.com/drugs/DB00110ApprovedInvestigationalPalivizumab is composed of to heavy chains (50.6 kDa each) and two light chains (27.6 kDa each), contains 1-2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF) … Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV).