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Displaying results 221 - 230 of 10000 in total
  1. Drug

    Turoctocog alfa

    go.drugbank.com/drugs/DB09109
    Approved

    Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally … Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any human- or animal-derived materials.

    Products: NovoEight 500IU Powder and Solvent for Solution for Injection, NovoEight 1000IU Powder and Solvent for Solution for Injection
  2. Drug

    Gadoteric acid

    go.drugbank.com/drugs/DB09132
    ApprovedInvestigational

    Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). … [A263141,A263106] Gadoterate is approved by the FDA under the brand name DOTAREM on 20th March 2013 for intravenous uses with magnetic resonance imaging (MRI) in the brain (intracranial), spine, and

    Categories: Compounds used in a research, industrial, or household settingSynonyms: [2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl-κ4N1,N4,N7,N10)tetraacetato(3−)]gadolinium
  3. Drug

    Ethanol

    go.drugbank.com/drugs/DB00898
    ApprovedInvestigational

    It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. … It has bactericidal activity and is used often as a topical disinfectant.

    Mixtures: RBX For Men Antibacterial Hand Sanitizer Aloe Vera and Tea Tree Scented, Vitaplus foreCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Esomeprazole

    go.drugbank.com/drugs/DB00736
    ApprovedInvestigational

    It can also be found in quadruple regimens for the treatment of _H. pylori_ infections along with other antibiotics including [DB01060], [DB01211], and [DB00916], for example. … Esomeprazole is the s-isomer of [DB00338], which is a racemate of the S- and R-enantiomer.

    Synonyms: Omeprazole S-formInternational brands: Cor
  5. Drug

    Bleomycin

    go.drugbank.com/drugs/DB00290
    ApprovedInvestigational

    It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin. … A complex of related glycopeptide antibiotics from <i>Streptomyces verticillus</i> consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0).

    Products: DBL BLEOMYCIN SULFATE FOR INJECTION 15000 iu/vial, Bleomycin for Injection
  6. Drug

    Chlorhexidine

    go.drugbank.com/drugs/DB00878
    ApprovedInvestigationalVet approvedWithdrawn

    [L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the early 1950s[A190474] and was introduced to the US in the 1970s. … Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.

    Synonyms: N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamideInternational brands: Prevacare R
  7. Pathway

    Fc Epsilon Receptor I Signaling in Mast Cells

    smpdb.ca/view/SMP0000358
    Signaling

    Fc epsilon receptor 1 (Fc epsilon RI) is a high-affinity receptor for the Fc region of immunoglobulin E (IgE), an antibody isotope involved in allergies. … The release of these compounds results in the inflammatory response.

    Drugs: Heparin · Calcium · Magnesium cation · Zinc · Prostaglandin D2 · Arachidonic Acid
    Enzymes: Linker for activation of T-cells family member 1
  8. Drug

    Nitroglycerin

    go.drugbank.com/drugs/DB00727
    ApprovedInvestigational

    [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and prevent angina.[A249970] Nitroglycerin causes vasodilation in both arteries and veins. … [A249965] Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced

    Mixtures: Nitroglycerin In 5% Dextrose Inj.-400mcg/ml, Nitroglycerin In 5% Dextrose Inj.-200mcg/mlCategories: Compounds used in a research, industrial, or household setting, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  9. Drug

    Risankizumab

    go.drugbank.com/drugs/DB14762
    ApprovedInvestigational

    [A254716] Risankizumab is used to treat plaque psoriasis, psoriatic arthritis, and Crohn's disease.[L39885,L44191,L44231] Risankizumab is being investigated for atopic dermatitis.[A254716] … [L39885] It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019.

    Products: SKYRIZI SOLUTION FOR INJECTION IN PRE-FILLED PEN 150MG/ML, SKYRIZI SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 75MG/0.83ML
  10. Drug

    Nystatin

    go.drugbank.com/drugs/DB00646
    ApprovedInvestigationalVet approved

    for systemic use. … in structure.

    Mixtures: BABYSKIN® N CREMA, BABYSKIN® N CREMACategories: Compounds used in a research, industrial, or household setting, Antifungals for Topical Use