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Displaying results 221 - 230 of 688 in total
  1. Drug

    Retlirafusp alfa

    go.drugbank.com/drugs/DB17517
    Investigational

  2. Drug

    Reveglucosidase alfa

    go.drugbank.com/drugs/DB17665
    Investigational

    Synonyms: , glycoform alfa, Reveglucosidase alfa
  3. Drug

    Efsubaglutide alfa

    go.drugbank.com/drugs/DB21757
    Investigational

    Synonyms: Efsubaglutide alfa
  4. Pathway

    Pyruvate Dehydrogenase Complex Deficiency

    smpdb.ca/view/SMP0000212
    Disease

    PDHA1 encodes the pyruvate dehydrogenase complex (PDC) a critical complex that converts pyruvate from glycolysis to acetyl CoA for the citric acid cycle. … Pyruvate dehydrogenase complex deficiency results from a mutation in the E1-alpha polypeptide gene (PDHA1).

    Drugs: Pyruvic acid · Biotin · Adenosine phosphate · Glutathione · NADH · ATP +13 more
    Enzymes: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
  5. Pathway

    Mitochondrial Complex II Deficiency

    smpdb.ca/view/SMP0000548
    Disease

    Interestingly, complex II deficiency gene mutation carriers may be at an increased risk for certain cancers. … Because complex II is found in the mitochondria, CII deficiency is technically considered a mitochondrial disease.

    Drugs: Pyruvic acid · Biotin · Succinic acid · NADH · ATP · Magnesium cation +4 more
    Enzymes: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
  6. Pathway

    Copper gluconate Drug Metabolism

    smpdb.ca/view/SMP0130548
    Metabolic

    Copper gluconate passes through the liver and is then excreted from the body mainly through the kidney. … Copper gluconate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Copper gluconate
  7. Drug

    ALT-801

    go.drugbank.com/drugs/DB15386
    Investigational

    ALT-801 is under investigation in clinical trial NCT01478074 (ALT-801-activated Natural Killer Cells After FLAG Induction for Acute Myeloid Leukemia).

  8. Drug

    Bemiltenase alfa

    go.drugbank.com/drugs/DB19303
    Experimental

    Synonyms: Bemiltenase alfa
  9. Drug

    Tabirafusp alfa

    go.drugbank.com/drugs/DB21764
    Investigational

    Synonyms: Tabirafusp alfa
  10. Drug

    Marzeptacog alfa (activated)

    go.drugbank.com/drugs/DB15278
    Investigational

    Marzeptacog alfa (activated) is under investigation in clinical trial NCT01439971 (Phase 1 Safety, Pharmacokinetics And Pharmacodynamics Study Of Recombinant Factor VIIa Variant (813d) In Adult Subjects

    Synonyms: Marzeptacog alfa (activated)