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Omega-3-carboxylic acids
go.drugbank.com/drugs/DB09568ApprovedWithdrawnThe increased bioavailability is explained because OM3-CA is found in a form of polyunsaturated free fatty acids as opposed to other products whose form is as ethyl esters. … The rest of the concentration is represented by docosapentaenoic acid and traces of some other components such as alpha-tocopherol, gelatin, glycerol, sorbitol and purified water.
Amiloxate
go.drugbank.com/drugs/DB11207ApprovedIt is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity [A32916].
Hydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigational[L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect. … [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus
Tapinarof
go.drugbank.com/drugs/DB06083ApprovedInvestigationalIt is available as a topical cream to be applied to the affected area once daily. … [L41845, A248790] Tapiranof was first discovered as a metabolite (3,5-dihydroxy-4-isopropylstilbene) produced in _Photorhabdus luminescens_, a gram-negative bacillus that lives symbiotically with the _
Methaqualone
go.drugbank.com/drugs/DB04833ApprovedIllicitWithdrawnIt has also been used illegally as a recreational drug, commonly known as Quaaludes, Sopors, Ludes or Mandrax (particularly in the 1970s in North America) depending on the manufacturer. … Its use peaked in the early 1970s as a hypnotic, sedative, and muscle relaxant commonly used for insomnia.
Norepinephrine
go.drugbank.com/drugs/DB00368ApprovedInvestigationalIt is also found in plants and is used pharmacologically as a sympathomimetic.
Procaine
go.drugbank.com/drugs/DB00721ApprovedInvestigationalVet approvedProcaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients [L1215].
Iodide I-123
go.drugbank.com/drugs/DB09420ApprovedInvestigationalRadioactive I-123 in particular is effective for this use as its half-life of approximately 13.13 h (hours) is ideal for the 24-h (hour) iodine uptake test and it has a reduced radiation burden as compared … Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease.
Uridine triacetate
go.drugbank.com/drugs/DB09144ApprovedAs a result, these metabolites are associated with various unpleasant side effects such as neutropenia, mucositis, diarrhea, and hand–foot syndrome. … It is provided in the prodrug form as uridine triacetate as this form delivers 4- to 6-fold more uridine into the systemic circulation compared to equimolar doses of uridine itself.
Peppermint
go.drugbank.com/drugs/DB10984ApprovedPeppermint allergenic extract is used in allergenic testing.
Mixtures: Naus-over