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Beeswax
go.drugbank.com/drugs/DB11600ApprovedThe wax obtained from the honeycomb of the bee. It consists primarily of myricyl palmitate, cerotic acid esters and some high-carbon paraffins. … Beeswax is used as a stiffening agent in ointments and creams, and enables water to be incorporated to produce water-in-oil emulsions.
Imelasomeran
go.drugbank.com/drugs/DB17090ApprovedInvestigationalImelasomeran was first approved in Canada on September 1, 2022, as one-half of Moderna's Spikevax Bivalent COVID-19 mRNA vaccine. It encodes for the viral spike protein of the Omicron BA.1 variant of SARS-CoV-2, a particularly infectious...
Ferric maltol
go.drugbank.com/drugs/DB15598ApprovedInvestigational[L10974] On December 22, 2025, the FDA expanded this indication to include pediatric patients aged 10 years and older. [L54873,L54878] … Ferric maltol is an iron(III) atom complexed with 3 maltol molecules to increase the bioavailability compared to iron(II), without depositing it in the duodenum as insoluble ferric hydroxide and phosphate
Categories: Blood and Blood Forming OrgansIcatibant
go.drugbank.com/drugs/DB06196ApprovedInvestigational[A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema. … [L49776,L49781] The FDA approval was based on positive results obtained from 3 double-blind, randomized, controlled clinical trials known as FAST 1, 2, and 3, where a median time to almost complete symptom
Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsProducts: İCATİN 30MG/3ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖRForkhead box protein M1
go.drugbank.com/bio_entities/BE0014280TargetHumansTranscription factor regulating the expression of cell cycle genes essential for DNA replication and mitosis (PubMed:19160488, PubMed:20360045).
Synonyms: Winged-helix factor from INS-1 cellsZeatin
go.drugbank.com/drugs/DB11337InvestigationalAn aminopurine factor in plant extracts that induces cell division. (Grant & Hackh's Chemical Dict, 5th ed)
Synonyms: (E)-2-methyl-4-(1H-purin-6-ylamino)but-2-en-1-olComplement C5
go.drugbank.com/bio_entities/BE0000855TargetHumansPrecursor of the C5a anaphylatoxin and complement C5b components of the complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that … Activated downstream of classical, alternative, lectin and GZMK complement pathways (PubMed:12878586, PubMed:18204047, PubMed:30643019, PubMed:39914456, PubMed:39814882, PubMed:6554279)
Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4Pozelimab
go.drugbank.com/drugs/DB15218ApprovedInvestigationalCD55-deficient protein-losing enteropathy (PLE), or CHAPLE disease, is an ultra-rare hereditary disease, with fewer than 100 patients diagnosed worldwide or fewer than 10 patients in the US. … Under normal circumstances, CD55 inhibits the activity of C3 and C5 convertases, thus preventing the cleavage of C3 and C5 respectively into immunoreactive peptides C3a and C5a.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsPatent Blue
go.drugbank.com/drugs/DB13967ApprovedInvestigationalPatent blue was developed by Guerbet and approved by Health Canada on December 31, 1979.[L1113] The isomer isosulphan is used in the United States for the same indications than patent blue.[A32574] … Patent blue is aniline dye and it is one of the most common dyes used.[A32573] It is a sodium or calcium salt of diethylammonium hydroxide inner salt.
Belzutifan
go.drugbank.com/drugs/DB15463ApprovedInvestigational[L35995] The HIF-2α protein was first identified in the 1990s by researchers at UT Southwestern Medical Center as a key player in the growth of certain cancers. … [L36000] It was later approved for the treatment of locally advanced, unresectable, or metastatic pheochromocytoma or paraganglioma (PPGL) in patients aged 12 years and older.[L49271]
Categories: Antineoplastic and Immunomodulating Agents