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Lomitapide
go.drugbank.com/drugs/DB08827ApprovedLomitapide, marketed under the brand names Juxtapid (USA) and Lojuxta (EU), is a first-in-class, small-molecule inhibitor of microsomal triglyceride transfer protein (MTP). … [A275445, A7367] This makes it a critical therapeutic option for "receptor-negative" patients who have little to no functional LDL receptor activity.
Synonyms: 9H-FLUORENE-9-CARBOXAMIDE, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)(1,1'-BIPHENYL)-2-YL)CARBONYL)AMINO)-1-PIPERIDINYL)BUTYL)-, N-(2,2,2-TRIFLUOROETHYL)-9-(4-(4-(((4'-(TRIFLUOROMETHYL)BIPHENYL-2-YL)CARBONYL)AMINO)PIPERIDIN-1-YL)BUTYL)-9H-FLUORENE-9-CARBOXAMIDECategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexMMDA
go.drugbank.com/drugs/DB01442ExperimentalIllicitMMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen.
Synonyms: 5-Methoxy-3,4-methylenedioxyamphetamine, 3-methoxy-methylenedioxyamphetamineCategories: Serotonin 5-HT2 Receptor Agonists, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesOrlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalIt was approved by the FDA for use in combination with a reduced-calorie diet in 1999. … [A229928] Orlistat is a lipase inhibitor used in the treatment of obesity that works by inhibiting fat-metabolizing enzymes.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: ORLISTAT EG, FINOBES ® 120 MG.Ferrous glycine sulfate
go.drugbank.com/drugs/DB14501ApprovedProducts: FERRO SANOL DUODENAL 100 MG KAPSUL, 20 ADET, FERRO SANOL DUODENAL 100 MG KAPSUL, 50 ADETAsfotase alfa
go.drugbank.com/drugs/DB09105ApprovedInvestigationalFood and Drug Administration (FDA) on October 23, 2015. Asfotase Alfa is marketed under the brand name Strensiq® by Alexion Pharmaceuticals, Inc. … Asfotase alfa was first approved by Pharmaceuticals and Medicals Devices Agency of Japan (PMDA) on July 3, 2015, then approved by the European Medicine Agency (EMA) on August 28, 2015, and was approved
Products: STRENSİQ 28 MG/0.7 ML ENJEKSİYONLUK ÇÖZELTİ, 12 ADET, STRENSİQ 40 MG/1.0 ML ENJEKSİYONLUK ÇÖZELTİ, 12 ADETPrasugrel
go.drugbank.com/drugs/DB06209ApprovedInvestigationalSimilar to clopidogrel, prasugrel is a prodrug that requires enzymatic transformation in the liver to its active metabolite, R-138727. … Prasugrel, a thienopyridine derivative, is a platelet activation and aggregation inhibitor structurally and pharmacologically related to clopidogrel and ticlopidine.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: SUGVİDA 10 MG FİLM KAPLI TABLET, 28 ADET, EFFIENT 10 MG FILM KAPLI TABLET, 28 ADETFerric carboxymaltose
go.drugbank.com/drugs/DB08917ApprovedInvestigationalIt was FDA approved on July 25, 2013.
Categories: Compounds used in a research, industrial, or household settingProducts: Ferapplic 500 mg/10 ml Enjeksiyonluk/İnfüzyonluk Çözelti, 5 flakon, Ferapplic 500 mg/10 ml Enjeksiyonluk/İnfüzyonluk Çözelti, 1 flakonPerindopril
go.drugbank.com/drugs/DB00790ApprovedInvestigationalIt is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. … Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).
Synonyms: (2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acidMixtures: Triveram 20 mg/10 mg/5 mg Filmtabletten, TRIVERAM FILM-COATED TABLET 20 mg/10 mg/5 mgCalcium acetate
go.drugbank.com/drugs/DB00258ApprovedIt has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Mixtures: OSVAREN 435 MG/235 MG 180 FILM KAPLI TABLET, DALIDOMEPOLVO SACHET 2.2 GCategories: ascorbic acid (vit C) and calcium, Compounds used in a research, industrial, or household settingDextromethorphan
go.drugbank.com/drugs/DB00514ApprovedInvestigational[A215412] Although similar in structure to other opioids, it has minimal interaction with opioid receptors.[A215412] Dextromethorphan was granted FDA approval before 3 December 1957. … Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse.
Synonyms: D-methorphanMixtures: BENICAL 10 MG+20MG+2MG/5 ML SURUP, 100 ML, DAYCOLD-HOT 500/10/15/100 MG SAŞE ,20 SAŞE