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Displaying results 2351 - 2360 of 3483 in total
  1. Drug

    Estradiol dienanthate

    go.drugbank.com/drugs/DB13955
    ApprovedVet approvedWithdrawn

    Estradiol Dienanthate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female s...

    Categories: Cytochrome P-450 CYP1A1 Substrates, P-glycoprotein substrates
  2. Drug

    Moroctocog alfa

    go.drugbank.com/drugs/DB13999
    Approved

    Activation of Factor IX leads to a cascade of signals that results in activation of Factor X, which then results in the conversion of prothrombin to thrombin, and as a result, leads to the conversion of

  3. Drug

    5-methoxy-N,N-dimethyltryptamine

    go.drugbank.com/drugs/DB14010
    IllicitInvestigational

    5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug, as well as dimethyltryp...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  4. Drug

    Clinafloxacin

    go.drugbank.com/drugs/DB14025
    Experimental

    Clinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties. However, its approval and release have been halted due to the presence of serious side effects.

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C19 Inhibitors
  5. Drug

    Madecassic acid

    go.drugbank.com/drugs/DB14037
    Investigational

    Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 CYP2D6 Inhibitors
  6. Drug

    Valinomycin

    go.drugbank.com/drugs/DB14057
    Experimental

    It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. … (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  7. Drug

    Concanamycin A

    go.drugbank.com/drugs/DB14062
    Experimental

    Concanamycin A is an H+-ATPase (vacuolar) inhibitor.

    Categories: P-glycoprotein inhibitors
  8. Drug

    Tetrandrine

    go.drugbank.com/drugs/DB14066
    Investigational

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  9. Drug

    Dofequidar

    go.drugbank.com/drugs/DB14067
    Investigational

    Dofequidar is an antineoplastic agent.

    Categories: P-glycoprotein inhibitors
  10. Drug

    HM-30181

    go.drugbank.com/drugs/DB14070
    Investigational

    Categories: P-glycoprotein inhibitors