HM-30181

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DB14070InvestigationalSmall molecule

HM-30181: Overview.

Mechanism: Pharmacologically active on ATP-dependent translocase ABCB1
Curator reviewed
Formula / weight: C₃₈H₃₆N₆O₇ · 688.741 g/mol (avg)
Also known as: Encequidar
Code names: HM-30181 · HM-30181A · HM30181AK · HM30181AK-US

Resolves to

Compound

UNIIK4I4I996O4CAS849675-66-7

Clinical / RWD

ATCL01CD51

Structure

InChIKeyAHJUHHDDCJQACA-UHFFFAOYSA-NSMILES[H]N(C(=O)C1=CC(=O)C2=CC=CC=C2O1)C1=CC(OC)=C(OC)C=C1C1=NN(N=N1)C1=CC=C(CCN2CCC3=CC(OC)=C(OC)C=C3C2)C=C1

Targets

P08183ABCB1P21439ABCB4

What you can answer from here — as of October 24, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

17Clinical trialsPhase, status and sponsor resolved per trial

1ATC codeIncluding every combination product, plus 7 drug categories

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with HM-30181, and which of those have an active Phase 3 trial?

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