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Sulfinpyrazone
go.drugbank.com/drugs/DB01138ApprovedA uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesSodium ascorbate
go.drugbank.com/drugs/DB14482ApprovedInvestigationalNutraceuticalMixtures: Virt-Pn DHA, V-NatalCategories: Compounds used in a research, industrial, or household settingAlfacalcidol
go.drugbank.com/drugs/DB01436ApprovedInvestigationalNutraceutical[A234044] It plays an essential function in calcium homeostasis and bone metabolism. … Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D].
Products: ONE-ALPHA 2 MCG/ML IV AMPUL, 10 ADET, ONE-ALPHA 1 MCG/0.5 ML IV AMPUL, 10 ADETOxabolone cipionate
go.drugbank.com/drugs/DB13185ExperimentalIt is considered as a performance enhancing drug thus is prohibited from use in sports. … Oxabolone cipionate is the C17β cypionate ester and a prodrug of [DB01500]. A synthetic anabolic-androgenic (AAS) steroid, it is a derivative of 19-nortestosterone (nandrolone).
Iproclozide
go.drugbank.com/drugs/DB09247ApprovedWithdrawnAlthough it was employed as an antidepressant for a time, the fact that the agent is capable of causing fulminant hepatitis and that its use has been documented as the cause for at least three reported … Iproclozide is an irreversible and selective hydrazine class based monoamine oxidase inhibitor (MAOI).
Taletrectinib
go.drugbank.com/drugs/DB18711ApprovedInvestigational[L53308] Gene fusions involving _ROS1_, a proto-oncogene, have been identified as oncogenic drivers in 1-2% of patients with non-small cell lung cancer (NSCLC), in addition to other cancers at variable … Taletrectinib is an orally available small molecule kinase inhibitor.
Categories: Cytochrome P-450 CYP1A2 Inducers, P-glycoprotein inhibitorsRibavirin
go.drugbank.com/drugs/DB00811ApprovedInvestigationalThe potential use of ribavirin as a treatment for acute myeloid leukemia is currently under investigation. … When used to treat Hepatitis C virus (HCV) infections, it is always used as a part of combination therapies as ribavirin monotherapy is not efficacious in the treatment of chronic hepatitis C infection
Products: RIBAVIRINA TEVA PHARMA BVOzenoxacin
go.drugbank.com/drugs/DB12924ApprovedAs of December 11, 2017 the FDA approved Ferrer Internacional S.A.' … s Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by *Staphylococccus aureus* or *Streptococcus pyogenes* in adult and pediatric patients 2 months of age
Delandistrogene moxeparvovec
go.drugbank.com/drugs/DB16802ApprovedInvestigational[L47026] DMD is an X-linked genetic disorder characterized by mutations in the dystrophin gene, leading to a deficiency in functional dystrophin protein. … Microdystrophin is a truncated, functional form of dystrophin.
Filgotinib
go.drugbank.com/drugs/DB14845ApprovedInvestigational[A189165] Non-selective JAK inhibitors like [tofacitinib] target JAK1 and JAK3 subtypes with minimal activity at JAK2. In contrast, the newly approved filgotinib is a highly selective JAK1 inhibitor. … Rheumatoid arthritis (RA) is a chronic, autoimmune, systemic, and inflammatory disease that causes synovial joint symptoms and can limit range of motion in severe cases.
Categories: P-glycoprotein substrates