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Displaying results 2381 - 2390 of 2674 in total
  1. Drug

    AdimrSC-2f

    go.drugbank.com/drugs/DB16436
    Investigational

    The AdimrSC-2f (SARS-CoV-2) vaccine is developed through Adimmune Corporation, the only influenza vaccine manufacturer with both EU GMP and US FDA certification in Asia[L30553].

  2. Drug

    Oseltamivir

    go.drugbank.com/drugs/DB00198
    ApprovedInvestigational

    Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activi...

  3. Drug

    VX-702

    go.drugbank.com/drugs/DB05470
    Investigational

    In the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA. … VX-702 is a small molecule investigational oral anti-cytokine therapy for treatment of inflammatory diseases, specifically rheumatoid arthritis (RA). It acts as a p38 MAP kinase inhibitor.

  4. Target

    Beta-galactosidase

    go.drugbank.com/bio_entities/BE0009999
    TargetEnzymeHumans

    Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans

    Synonyms: Elastin receptor 1
  5. Drug

    Pimicotinib

    go.drugbank.com/drugs/DB18972
    Investigational

    [L53748] Pimicotinib was granted Fast Track Designation in December 2023 by the FDA. [L53753]

  6. Target

    C-type lectin domain family 14 member A

    go.drugbank.com/bio_entities/BE0005467
    TargetHumans

    Synonyms: Epidermal growth factor receptor 5
  7. Drug

    Satraplatin

    go.drugbank.com/drugs/DB04996
    Investigational

    Food and Drug Administration (FDA) approval and is not available in retail pharmacies.

  8. Target

    Vitamin B12 transporter BtuB

    go.drugbank.com/bio_entities/BE0001470
    TargetTransporterEscherichia coli (strain K12)

    Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space (PubMed:4579869). It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.

    Synonyms: Cobalamin receptor
  9. Target

    Neuropilin-1

    go.drugbank.com/bio_entities/BE0002129
    TargetHumans

    Cell-surface receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system.

    Synonyms: Vascular endothelial cell growth factor 165 receptor
  10. Target

    T-cell surface glycoprotein CD3 zeta chain

    go.drugbank.com/bio_entities/BE0003458
    TargetHumans

    When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z.

    Synonyms: T-cell receptor T3 zeta chain