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Rhein
go.drugbank.com/drugs/DB13174ExperimentalRhein is an anthraquinone metabolite of rheinanthrone and senna glycoside is present in many medicinal plants including Rheum palmatum, Cassia tora, Polygonum multiflorum, and Aloe barbadensis . It is known to have hepatoprotective, neph...
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsBamifylline
go.drugbank.com/drugs/DB13203InvestigationalBamifylline is a selective A1 adenosine receptor antagonist.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesBencyclane
go.drugbank.com/drugs/DB13488ExperimentalA vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects. Its mechanism may involve block of calcium channels.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesIodoform
go.drugbank.com/drugs/DB13813ApprovedInvestigationalVet approvedWithdrawnIodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. It is a relatively water-insoluble yellow solid that is chemically reactive in free-radical reactions . Due to its antimicrobial properties ...
Pipemidic acid
go.drugbank.com/drugs/DB13823InvestigationalPipemidic acid is a quinolone antibacterial agent with activity against various gram-positive and gram-negative bacteria.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsPhloxine B
go.drugbank.com/drugs/DB13911ApprovedWithdrawnPhloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing tablets. These tablets ...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsPiperaquine
go.drugbank.com/drugs/DB13941ApprovedInvestigationalPiperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China . Its use declined in the 1980's as piperaquine resistant strains of Plasmodium falciparum appeared and artemisinin derivatives became availab...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsTenofovir
go.drugbank.com/drugs/DB14126InvestigationalTenofovir is an acyclic nucleotide diester analog of adenosine monophosphate. In the most strict sense and due to the fact that it presents a phosphate group bound to the nitrogenous base, it is determined as an actual nucleotide analog....
Categories: P-glycoprotein substratesHydrocortisone butyrate
go.drugbank.com/drugs/DB14540ApprovedVet approvedCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InducersHydrocortisone probutate
go.drugbank.com/drugs/DB14543ApprovedVet approvedCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inducers