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Erlotinib
go.drugbank.com/drugs/DB00530ApprovedInvestigationalIt is typically marketed under the trade name Tarceva. … Erlotinib binds to the epidermal growth factor receptor (EGFR) tyrosine kinase in a reversible fashion at the adenosine triphosphate (ATP) binding site of the receptor.
Products: PMS-erlotinib, Erlocip 25mg Film Coated TabletDonepezil
go.drugbank.com/drugs/DB00843ApprovedInvestigational[L41125] Though it does not alter the progression of Alzheimer's disease, donepezil is effective in managing the symptoms of its associated dementia.[T668] … Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia.
Products: DONEPEZIL-HCL - CT 10MG, TABLET 10MGNicotine
go.drugbank.com/drugs/DB00184ApprovedInvestigationalIt is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission.
Products: Nicorette Invisi Transdermal Patch 10mg/16 hours, Nicorette Invisi Transdermal Patch 15mg/16 hoursErythromycin
go.drugbank.com/drugs/DB00199ApprovedInvestigationalVet approvedIt was originally discovered in 1952.[L5245] Erythromycin is widely used for treating a variety of infections, including those caused by gram-positive and gram-negative bacteria. … [L5245,L7261] It is available for administration in various forms, including intravenous, topical, and eye drop preparations.[L5245]
Mixtures: T-stat Pad-lot, Benzamycin PakProducts: Emycin Ect 250mg, Eryson Granules 400mg/5mlCiprofloxacin
go.drugbank.com/drugs/DB00537ApprovedInvestigational[A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections. … Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics.
Products: . - Liq 10mg/ml, Cipro IV 10mg/mlPantoprazole
go.drugbank.com/drugs/DB00213ApprovedInvestigationalIt can also be found in quadruple regimens for the treatment of _H. pylori_ infections along with other antibiotics including [amoxicillin], [clarithromycin], and [metronidazole], for example. … [A177577, A177580] Pantoprazole doses should be slowly lowered, or tapered, before discontinuing as rapid discontinuation of PPIs such as pantoprazole may cause a rebound effect and a short term increase
Products: PANTOPRAZOL - CT 20MG, PANTOPRAZOL - CT 40MGSelegiline
go.drugbank.com/drugs/DB01037ApprovedInvestigationalVet approvedIt is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. … It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.
Products: SELEGILIN STADA 10MG, SELEGILIN HEXAL 10MG TABLBromhexine
go.drugbank.com/drugs/DB09019ApprovedInvestigationalIt was introduced into the market in 1963, and is widely available as an over-the-counter drug in many countries. … It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough.
Mixtures: PENBRITIN EX, GRIPOFEN-T®Products: BUCOLYN 20MG/G POWDER, PAX KIDS®Prochlorperazine
go.drugbank.com/drugs/DB00433ApprovedInvestigationalVet approved[label] It mainly works by depressing the chemoreceptor trigger zone and blocking D2 dopamine receptors in the brain. It was shown to also block histaminergic, cholinergic and noradrenergic receptors. … [L6637] Prochlorperazine was first developed in the 1950s [L6643] and was first approved by the FDA in 1956.
Products: PMS-prochlorperazine Tab 10mg, PMS-prochlorperazine Suppositoires 10mgCytarabine
go.drugbank.com/drugs/DB00987ApprovedInvestigationalIt also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
Products: ALEXAN 40MG/2ML, Cytarabine-pws 100mg/vial