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Treprostinil
go.drugbank.com/drugs/DB00374ApprovedInvestigationalHowever, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room temperature. … [L41860] It is available in the following routes of administration: subcutaneous, intravenous, inhaled and oral. The first generic form of treprostinil became available in 2019.[A248775]
Categories: Prostaglandins I, Cytochrome P-450 SubstratesProducts: REMODULIN 5 mg/ml Infusionslösung, Treposa 5 mg/ml InfusionslösungLoratadine
go.drugbank.com/drugs/DB00455ApprovedInvestigational[A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations. … Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis.
Mixtures: Clarinase 5 mg/ 120 mg Retardtabletten, LORATADINA+ PSEUDOEFEDRINA0.5 MG + 6 MG/ML SOLUCION PEDIATRICACategories: P-glycoprotein inhibitors, P-glycoprotein substratesGranisetron
go.drugbank.com/drugs/DB00889ApprovedInvestigationalA serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Categories: Serotonin 5-HT3 Receptor Antagonists, Antiemetic Serotonin 5-HT3 Receptor AntagonistsProducts: GRANIDUR 3 MG/3 ML ENJEKSIYONLUK ÇÖZELTI, 5 ADET, KYTRIL 2 MG FİLM KAPLI TABLET, 5 ADETSugammadex
go.drugbank.com/drugs/DB06206ApprovedInvestigationalSugammadex (brand name Bridion) is marketed by Merck Sharp and Dohme, and was approved by the United States FDA on December 15, 2015. … Sugammadex provides a new treatment option to reverse the effects of those medications and possibly help patients recover sooner post-surgery.
Categories: Compounds used in a research, industrial, or household settingProducts: Sugammadex Aguettant 50 mg/ml Injektionslösung in einer Fertigspritze, SUGAMMADEX EGNitazoxanide
go.drugbank.com/drugs/DB00507ApprovedInvestigationalVet approvedNitazoxanide is a first-line, standard treatment for illness caused by C. parvum or G. lamblia infection in healthy (not immunosuppressed) adults and children and may also be considered in the treatment … microaerophilic bacteria, in addition to viruses.
Categories: Heterocyclic Compounds, 1-RingProducts: N/a, VIBATRIN® 100 MG / 5 MLAripiprazole
go.drugbank.com/drugs/DB01238ApprovedInvestigational[L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism of alpha-adrenergic and 5-HT2A receptors. … [L45859,A4393] Aripiprazole was given FDA approval on November 15, 2002.[L6136]
Categories: Serotonin 5-HT1 Receptor Agonists, Serotonin 5-HT1 Receptor AntagonistsProducts: ARIPIPRAZOLO EG, MENXELTI ® 5 MGAtracurium
go.drugbank.com/drugs/DB13295ApprovedInvestigationalWithdrawnCategories: Heterocyclic Compounds, 2-RingProducts: TRACRİUM 50 MG/5 ML ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 5 ADET, NEUCURIUM 50 MG/5 ML IV INFUZYON VE ENJEKSIYON ICIN COZELTI ICEREN AMPUL, 5 ADETTemozolomide
go.drugbank.com/drugs/DB00853ApprovedInvestigationalIt is currently marketed under the trademark TEMODAR® by Merck.[L32033] … [A229853, A229888, A229923, L32033] Following initial hydrolysis, further reactions liberate a highly reactive methyl diazonium cation capable of methylating various residues on adenosine and guanine bases
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substratesSynonyms: 3-methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide, 8-carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-oneCefprozil
go.drugbank.com/drugs/DB01150ApprovedInvestigationalCefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Categories: Heterocyclic Compounds, 2-RingProducts: SEROL 250 MG/5 ML ORAL SÜSPANSIYON IÇIN TOZ ,60 ML, SEROL 250 MG/5 ML ORAL SÜSPANSIYON IÇIN TOZ ,100 MLHydrogenated soybean oil
go.drugbank.com/drugs/DB11302ApprovedExtracted from the seeds of the soybean (Glycine soja), hydrogenated soybean oil is a major food fat used in the production of margarine, shortening, and salad and cooking oils. … Linolenic acid and stearic acids are contained in hydrogenated soybean oil, but hydrogenation results in reduced unsaturation in linolenic acid.
Products: S Balloon Slim Body Line