Search
Rifaximin
go.drugbank.com/drugs/DB01220ApprovedInvestigationalsyndrome (IBS-D) in adult women and men. … It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of overt hepatic encephalopathy recurrence; as well as diarrhea-predominant irritable bowel
Categories: Heterocyclic Compounds with 4 or More RingsEstrone
go.drugbank.com/drugs/DB00655ApprovedEstrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. … It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione.
Categories: Sex Hormones and Modulators of the Genital SystemSynonyms: 3-Hydroxy-1,3,5(10)-estratrien-17-oneTipiracil
go.drugbank.com/drugs/DB09343ApprovedInvestigationalor anti-EGFR therapy. … It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. The main function of Tipiracil in TAS-102 is to increase trifluridine bioavailability by inhibiting its catabolism.
Botulinum toxin type A
go.drugbank.com/drugs/DB00083ApprovedInvestigational[A231819,L32569] A popular use for Botox is the treatment of facial wrinkles and lines, however, there are many uses for the botulinum toxin A in the treatment of dystonia, incontinence, migraine, blepharospasm … In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use.
Products: BOTOX®200 U, SIAX ® 50 ULactulose
go.drugbank.com/drugs/DB00581ApprovedInvestigational[L6202] Nevertheless, although lactulose received formal FDA approval in 1977 and has since become a readily available generic and brand-name non-prescription medication listed on the World Health … or refuted via clinical investigation.
Synonyms: 4-O-beta-D-Galactopyranosyl-D-fructose, 4-O-beta-D-Galactopyranosyl-D-fructofuranoseMetipranolol
go.drugbank.com/drugs/DB01214ApprovedWithdrawnIt is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.
Categories: Beta Blocking Agents, Non-Selective, and ThiazidesRavulizumab
go.drugbank.com/drugs/DB11580ApprovedInvestigational[A244465] Ravulizumab was first approved by the FDA on December 21, 2018, for the treatment of paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome in children and adults. … [A244465] It was later approved by the European Commission on July 2, 2019, for the same indications.[L39710] Ravulizumab is also used to treat myasthenia gravis.
Rolitetracycline
go.drugbank.com/drugs/DB01301ApprovedWithdrawnA pyrrolidinylmethyl tetracycline.
Synonyms: N-(Pyrrolidinomethyl)tetracycline, N-(1-Pyrrolidinylmethyl)-tetracyclineCategories: combinations of tetracyclinesNorgestrel
go.drugbank.com/drugs/DB09389ApprovedNorgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel. However, only the levorotary enantiomer ([levonorgestrel]) is biologically active. … Norgestrel is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception.
Categories: Sex Hormones and Modulators of the Genital SystemSynonyms: 17-ethynyl-17-hydroxy-18a-homoestr-4-en-3-oneVorasidenib
go.drugbank.com/drugs/DB17097ApprovedInvestigational[A264209] Vorasidenib was first approved by the FDA on August 6, 2024, for the treatment of Grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1 or IDH2 mutation.[L51144] … [A264209] It works by suppressing the levels of D-2-hydroxyglutarate (2-HG), an oncometabolite produced by mutant IDH1 and IDH2 isoforms.