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Displaying results 2431 - 2440 of 2744 in total
  1. Drug

    Sulfapyridine

    go.drugbank.com/drugs/DB00891
    ApprovedWithdrawn

    Antibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed.

    Categories: Genito Urinary System and Sex Hormones
  2. Target

    Proteasome subunit alpha type-3

    go.drugbank.com/bio_entities/BE0003912
    TargetHumans

    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).

    Synonyms: Multicatalytic endopeptidase complex subunit C8
  3. Drug

    Linaprazan

    go.drugbank.com/drugs/DB20602
    Investigational

    The usage of the INN stem '-prazan' in the name indicates that Linaprazan is a proton pump inhibitor, not dependent on acid activation.

  4. Drug

    Prusogliptin

    go.drugbank.com/drugs/DB20606
    Investigational

    The usage of the INN stem '-gliptin' in the name indicates that Prusogliptin is a dipeptidyl aminopeptidase-IV inhibitor.

  5. Drug

    Amsilarotene

    go.drugbank.com/drugs/DB21085
    Investigational

    The usage of the INN stem '-arotene' in the name indicates that Amsilarotene is a arotinoid derivative.

  6. Drug

    Guretolimod

    go.drugbank.com/drugs/DB21487
    Investigational

    The usage of the INN stem '-tolimod' in the name indicates that Guretolimod is a toll-like receptor (TLR) agonist.

  7. Drug

    Ocedurenone

    go.drugbank.com/drugs/DB21519
    Investigational

    The usage of the INN stem '-renone' in the name indicates that Ocedurenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist.

  8. Drug

    Selnoflast

    go.drugbank.com/drugs/DB21522
    Investigational

    The usage of the INN stem '-noflast' in the name indicates that Selnoflast is a inflammasome protein NLRP3 inhibitor.

  9. Drug

    Zastaprazan

    go.drugbank.com/drugs/DB21524
    Investigational

    The usage of the INN stem '-prazan' in the name indicates that Zastaprazan is a proton pump inhibitor, not dependent on acid activation.

  10. Drug

    Brimarafenib

    go.drugbank.com/drugs/DB21706
    Investigational

    The usage of the INN stem '-rafenib' in the name indicates that Brimarafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor.