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Pasireotide
go.drugbank.com/drugs/DB06663ApprovedInvestigationalPasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Synonyms: cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L- phenylalanyl-)Products: SIGNIFOR® 0.6 MG/ML SOLUCION INYECTABLE, SIGNIFOR® 0.9 MG/ML SOLUCION INYECTABLEGabapentin enacarbil
go.drugbank.com/drugs/DB08872ApprovedGabapentin enacarbil is marketed under the name Horizant. It is a prodrug of gabapentin, and indicated in adults for the treatment of Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN).
Pilocarpine
go.drugbank.com/drugs/DB01085ApprovedInvestigationalA naturally occurring alkaloid derived from the _Pilocarpus_ plants, pilocarpine is a muscarinic acetylcholine agonist. … [A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors.
Synonyms: 2(3H)-FURANONE, 3-ETHYLDIHYDRO-4-((1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-, (3S-CIS)-Products: PIL OFTENO, PILOMIN %2, 5 ML DAMLAAtidarsagene autotemcel
go.drugbank.com/drugs/DB17538ApprovedInvestigational[L45196] It was granted FDA approval under the brand name Lenmeldy in March 2024.[L50256] … [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic
Rifaximin
go.drugbank.com/drugs/DB01220ApprovedInvestigationalIt is marketed under the brand name Xifaxan by Salix Pharmaceuticals. … It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of overt hepatic encephalopathy recurrence; as well as diarrhea-predominant irritable bowel
Synonyms: Rifamycin L 105, Rifamycin L 105SVProducts: Colidimin 200 mg/10 ml - Granulat für orale SuspensionXenon Xe-129
go.drugbank.com/drugs/DB17386ApprovedInvestigationalHyperpolarized Xenon-129 (Xe-129) is a contrast agent used in the lung's clinical magnetic resonance imaging (MRI). … [L44528] Hyperpolarized Xe-129 is chemically identical to non-polarized Xe-129, and xenon is a clear, colorless, monoatomic, inert, stable, noble gas.[L44523]
Asenapine
go.drugbank.com/drugs/DB06216ApprovedInvestigationalIt is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009. … Developed by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with
Cinnamon oil
go.drugbank.com/drugs/DB15986ApprovedInvestigationalMixtures: AXE BRAND HEAT OILSynonyms: Cassia oil, Cinnamon oilRetapamulin
go.drugbank.com/drugs/DB01256ApprovedRetapamulin, marketed by GlaxoSmithKline as the ointment Altabax, is an antibiotic for skin infections like impetigo. It was approved by the FDA in April 2007.
Sofosbuvir
go.drugbank.com/drugs/DB08934ApprovedInvestigationalIts use has also proven successful in the treatment of HCV in patients co-infected with HIV [A19627]. … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852].
Synonyms: S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)- (phenoxy)phosphorylamino)propanoateProducts: I-HEP SOBOVIR