Search
Benzphetamine
go.drugbank.com/drugs/DB00865ApprovedIllicitA sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: RecedeSuprofen
go.drugbank.com/drugs/DB00870ApprovedWithdrawnAn ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Synonyms: p-2-thenoylhydratropic acid, (±)-2-(p-(2-thenoyl)phenyl)propionic acidCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsSirolimus
go.drugbank.com/drugs/DB00877ApprovedInvestigationalSirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria Streptomyces hygroscopicus, which was isolated from the soil of the Vai Atari region of Rapa Nui (Easter Island). It was first isolated and iden...
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: P-HYSPLAN, RENACEPTGranisetron
go.drugbank.com/drugs/DB00889ApprovedInvestigationalA serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesFamotidine
go.drugbank.com/drugs/DB00927ApprovedInvestigational[L11166] Compared to other H<sub>2</sub> receptor antagonists, famotidine displays high selectivity towards this receptor; in a study consisting of healthy volunteers and patients with acid hypersecretory … Famotidine is a competitive histamine-2 (H<sub>2</sub>) receptor antagonist that works to inhibit gastric acid secretion.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsFluconazole
go.drugbank.com/drugs/DB00196ApprovedInvestigationalFluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifun...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigationalCitalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertia...
Categories: Serotonin Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsNevirapine
go.drugbank.com/drugs/DB00238ApprovedInvestigationalA potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyr...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersButalbital
go.drugbank.com/drugs/DB00241ApprovedIllicitButalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. It is a short-to-intermediate acting member of barbiturates t...
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSulfanilamide
go.drugbank.com/drugs/DB00259ApprovedWithdrawnSulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Synonyms: p-aminobenzenesulfamide, p-aminobenzenesulfonamideCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors