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Carboplatin
go.drugbank.com/drugs/DB00958ApprovedInvestigationalCarboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982. … [A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248]
Categories: Compounds used in a research, industrial, or household settingSynonyms: Cis-(1,1-cyclobutanedicarboxylato)diammineplatinum(II), Cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II)Methylene blue
go.drugbank.com/drugs/DB09241ApprovedInvestigationalHistorically, it has been widely used in Africa to treat malaria, but now it disappeared when chloroquine (CQ) and other drugs entered the market. … Methylthioninium chloride (INN, or methylene blue, proposed trade name Rember) is an investigational drug being developed by the University of Aberdeen and TauRx Therapeutics that has been shown in early
Mixtures: UR N-C Urinary AntisepticProducts: Methylene Blue INJ, Methylene Blue Inj 1%Selenium Sulfide
go.drugbank.com/drugs/DB00971ApprovedSelenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent … Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea.
Synonyms: Selenium(IV) sulfide, Selenium(IV) disulfideProducts: Selsun Blue 2-in-1, Selsun Blue, 2-IN-1Pamidronic acid
go.drugbank.com/drugs/DB00282ApprovedInvestigationalPamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid] and [alendronic acid].[A203111] Pamidronic acid was first described in the literature in 1977. … [A203111] Pamidronic acid was granted FDA approval on 31 October 1991.[L13835]
Products: Aredia Liq Inj 3mg/ml, PAMEX 90 MG IV INF. ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADETProtamine sulfate
go.drugbank.com/drugs/DB09141ApprovedInvestigationalSince it's earliest discovery in salmon rine sperm heads in the late 1800's to its formal introduction via US FDA approval in 1939, protamine sulfate has occupied an important therapeutic niche as perhaps … Regardless, protamine sulfate continues to see contemporary use given its genuine effectiveness in reversing heparin effects.
Products: Protamine Sulfate Inj 10mg/ml USP, PROLFAT 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADETIncreases in total cholesterol
go.drugbank.com/conditions/DBCOND0101889Drugs: PitavastatinSynonyms: Increases in total cholesterolOxytocin
go.drugbank.com/drugs/DB00107ApprovedInvestigationalVet approved[A229108,A229113] It is estimated that labor induction with oxytocin is used in almost 10% of deliveries globally. … Dale first identified oxytocin and its uterine contractile properties in 1906.
Products: Oxyla 10 IU/mL Injection, Oxytocin Inj 10unit/ml USPMepolizumab
go.drugbank.com/drugs/DB06612ApprovedInvestigationalThe pathogenesis of eosinophilia is complex, but IL-5 is recognized as a key cytokine involved in the differentiation, recruitment, activation, and prolonged survival of eosinophils in peripheral tissue … [A221048, A221053, A221058, A221063, A221068, L16518] Mepolizumab is a fully-humanized recombinant IgG1 kappa monoclonal antibody directed against IL-5 produced in Chinese hamster ovary cells.
Products: NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML, NUCALA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100MG/MLPhenytoin
go.drugbank.com/drugs/DB00252ApprovedInvestigationalVet approved[A188826,A188832] Clinicians are advised to initiate therapeutic drug monitoring in patients who require phenytoin since even small deviations from the recommended therapeutic range can lead to suboptimal … Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants.
Products: FENTEC-I, PHENYTOİN SODYUM MERCURY 50 mg/ml IM/IV ENJEKSİYONLUK ÇÖZELTİInsulin detemir
go.drugbank.com/drugs/DB01307ApprovedInvestigationalinsulin, and in the long term, damage to pancreatic islet cells. … [A2358, A2359, A2360, A44] If left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis
Categories: Drugs Used in DiabetesProducts: Levemir FlexPen 100U/ML Solution for injection in a prefilled pen, Levemir® FlexPen® 100 U/ml Solution for Injection in Pre-filled Pen