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Balsam of Peru
go.drugbank.com/drugs/DB11482ApprovedNutraceuticalVet approvedBalsam of Peru is a resin that comes from the tree Myroxylon balsamum pereirae. It is constituted by a mixture of substances from which the major components are benzyl cinnamate and [DB00676]. … [L1113] By the EMA, the balsam of Peru is approved and categorized under the herbal medicine products.[F121]
Mixtures: PainAway with natural peppermint and Balsam Peru, balsam peru oil PainAway with natural peppermint and Balsam PeruFenoldopam
go.drugbank.com/drugs/DB00800ApprovedA dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.
Categories: Adrenergic and Dopaminergic AgentsAmivantamab
go.drugbank.com/drugs/DB16695ApprovedInvestigationalAmivantamab, also known as JNJ-61186372, is an anti-EGFR-MET bispecific antibody, derived from Chinese hamster ovary cells, approved for the treatment of adult patients with locally advanced or metastatic … [A235133] Amivantamab was granted FDA approval on 21 May 2021,[L34193] followed by the approval by the EMA on 9 December 2021 [L41474] and Health Canada on 30 March 2022.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsThromboembolism
go.drugbank.com/conditions/DBCOND0022145Synonyms: Embolism and thrombosis of unspecified siteMaftivimab
go.drugbank.com/drugs/DB15899ApprovedInvestigationalINMAZEB™ is produced by Regeneron Pharmaceuticals and was granted FDA approval on October 14, 2020.[L17320] … All three mAbs bind to a distinct portion of the GP<sub>1,2</sub> glycoprotein and collectively provide neutralizing and Fc-mediated immune effector function against EBOV _in vitro_ and protection against
Categories: Amino Acids, Peptides, and ProteinsTyrosine
go.drugbank.com/drugs/DB00135ApprovedInvestigationalNutraceuticalIn animals it is synthesized from [phenylalanine]. It is also the precursor of [epinephrine], thyroid hormones, and melanin.
Categories: Amino Acids, Peptides, and ProteinsEcallantide
go.drugbank.com/drugs/DB05311ApprovedApart from its FDA and EMA indication, ecallantide has been used off label in the management of nonhistaminergic angioedema, not due to HAE [A32017]. … Ecallantide is marketed by FDA and EMA under the trade name Kalbitor for subcutaneous injection.
Categories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsElexacaftor
go.drugbank.com/drugs/DB15444ApprovedInvestigational[A187361] Elexacaftor, along with [VX-659], was designed to fill the need for an efficacious CF therapy for patients who are heterozygous for _F508del-CFTR_ and a gene that does not produce protein or … [A187361] It received FDA approval in October 2019 in combination with [tezacaftor] and [ivacaftor] as the combination product Trikafta<sup>TM</sup>.
Categories: ivacaftor, tezacaftor and elexacaftorClotiazepam
go.drugbank.com/drugs/DB01559ApprovedIllicitClotiazepam is a thienodiazepine, not approved for sale in the U.S. or Canada, but has been approved in the U.K. It is a schedule IV drug in Canada.
Categories: Benzodiazepines and benzodiazepine derivativesSPARC
go.drugbank.com/bio_entities/BE0002145TargetHumansBinds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. … There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity
Synonyms: Secreted protein acidic and rich in cysteine