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Displaying results 2531 - 2540 of 6951 in total

Drug
Lofexidine
go.drugbank.com/drugs/DB04948
ApprovedInvestigational
Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of opioid withdrawal in the United Kingdom in 1992. … [A33084] It was first studied for use as an antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment of hypertension than clonidine.
Categories: Serotonin Receptor Agonists, Adrenergic alpha-2 Receptor Agonists
Drug
Cobicistat
go.drugbank.com/drugs/DB09065
ApprovedInvestigational
Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). … Increasing systemic exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and a decreased side effect profile.
Categories: Antiinfectives for Systemic Use, Antivirals used in combination for the treatment of HIV infections
Drug
Magnesium citrate
go.drugbank.com/drugs/DB11110
ApprovedInvestigational
[T215] Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug products under the specifications of oral administration of a maximum concentration of 237 mg.
Categories: Drugs for Constipation
Drug
Pargyline
go.drugbank.com/drugs/DB01626
Approved
Pargyline is a monoamine oxidase inhibitor with antihypertensive properties.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
Drug
Parathyroid hormone
go.drugbank.com/drugs/DB05829
ApprovedInvestigational
Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing ...
Drug
Mineral oil
go.drugbank.com/drugs/DB11057
ApprovedInvestigationalVet approved
It is also used as a mild laxative for human or veterinary uses.
Categories: Drugs for Constipation
Drug
Cabozantinib
go.drugbank.com/drugs/DB08875
ApprovedInvestigational
for the treatment of hepatocellular carcinoma in previously treated patients. … It was initially approved in the US under the brand name Cometriq, which is indicated for the treatment of metastatic medullary thyroid cancer.
Categories: Receptor Protein-Tyrosine Kinases, antagonists & inhibitors
Drug
Polidocanol
go.drugbank.com/drugs/DB06811
ApprovedInvestigational
The formula for Polidocanol has the structural formula C12H25(OCH2CH2)nOH, a mean extent of polymerization (n) of approximately 9 and a mean molecular weight of approximately 600.
Categories: Sclerosing Agents for Local Injection
Drug
Corticorelin ovine triflutate
go.drugbank.com/drugs/DB09067
Approved
It provides a differential diagnosis for Cushing's disease (a pituitary source of ACTH excess) or of ectopic ACTH syndrome (an ectopic source of ACTH excess).
Categories: Tests for Pituitary Function
Drug
Difluprednate
go.drugbank.com/drugs/DB06781
ApprovedInvestigational
It is indicated for treatment of endogenous anterior uveiti. … Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate.