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Displaying results 2541 - 2550 of 10000 in total
  1. Target

    Zinc transporter ZIP4

    go.drugbank.com/bio_entities/BE0009894
    TransporterHumans

    Also exhibits polyspecific binding and transport of Cu(2+), Cd(2+) and possibly Ni(2+) but at higher concentrations (PubMed:22242765, PubMed:31914589) … Plays an essential role for dietary zinc uptake from small intestine (By similarity). The Zn(2+) uniporter activity is regulated by zinc availability (PubMed:17202136, PubMed:32348750).

    Synonyms: Zrt- and Irt-like protein 4
  2. Target

    Zinc transporter ZIP3

    go.drugbank.com/bio_entities/BE0009904
    TransporterHumans

    Mediates Zn(2+) reuptake from the secreted milk within the alveolar lumen … Mediates the influx of Zn(2+) into cells from extracellular space. Controls Zn(2+) accumulation into dentate gyrus granule cells in the hippocampus.

    Synonyms: Zrt- and Irt-like protein 3
  3. Target

    Zinc transporter ZIP9

    go.drugbank.com/bio_entities/BE0009905
    TransporterHumans

    This pathway contributes to CLDN1 and CLDN5 expression and tight junction formation between adjacent Sertoli cells (By similarity). … Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis (PubMed:19420709, PubMed:25014355, PubMed:28219737).

    Synonyms: Zrt- and Irt-like protein 9
  4. Drug

    Gastric intrinsic factor

    go.drugbank.com/drugs/DB09349
    Approved

    However, it is currently in the marketed (but unapproved) product Hematogen in combination with cyanocobalamin (synthetic Vitamin B12), ferrous fumarate, and ascorbic acid for the treatment of anemias … Intrinsic factor is not currently available in any FDA or Health Canada approved products.

    Mixtures: Iron Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Calcium Threonate and Succinic AcidCategories: Amino Acids, Peptides, and Proteins
  5. Drug

    Insulin detemir

    go.drugbank.com/drugs/DB01307
    ApprovedInvestigational

    Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. … [A2358, A2359, A2360, A44] Insulin is released from the pancreas following a meal to promote the uptake of glucose from the blood into internal organs and tissues such as the liver, fat cells, and skeletal

    Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsProducts: 100 U/ML, Levemir® FlexPen® 100 U/ml Solution for Injection in Pre-filled Pen
  6. Drug

    Cupric sulfate

    go.drugbank.com/drugs/DB06778
    Approved

    Data from clinical observations of the neurotoxic effects of copper may provide the basis for future treatments affecting copper and its homeostasis [L1830]. … Cupric sulfate is a salt created by treating cupric oxide with sulfuric acid.

    Mixtures: Pnv-VP-U, Multivitamins and Minerals Tablets
  7. Drug

    Benzoin resin

    go.drugbank.com/drugs/DB11222
    Approved

    There are two common kinds of benzoin, benzoin Siam and benzoin Sumatra, that are obtained from different species of the _Styrax_ tree. … Benzoin resin is a balsamic resin obtained from the bark of several species of trees in the genus _Styrax_.

  8. Drug

    Stem bromelain

    go.drugbank.com/drugs/DB12249
    Approved

    This action allows bromelain to demonstrate a wide range of therapeutic benefits ranging from cardiovascular to anticancer therapy - but the specific mechanisms of action by which it can elicit these effects … The primary therapeutic use for which stem bromelain is currently and formally indicated is as a burn wound eschar debridement agent that has been approved by the EMA since 2012 and marketed under the

    Categories: Enzymes and Coenzymes
  9. Drug

    Berdazimer

    go.drugbank.com/drugs/DB18712
    Approved

    , and fear and anxiety in the pediatric population. … [A262965] On Jan 05, 2024, the FDA approved berdazimer under the brand name ZELSUVMI for the treatment of adult and pediatric molluscum contagiosum, and it is the first drug to be approved for this

  10. Target

    Interphotoreceptor matrix proteoglycan 2

    go.drugbank.com/bio_entities/BE0004942
    TargetHumans

    Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor

    Synonyms: Sialoprotein associated with cones and rods proteoglycan