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Human C1-esterase inhibitor
go.drugbank.com/drugs/DB06404ApprovedInvestigational[L16586, L16606] This drug is indicated for prophylaxis and treatment of Hereditary Angioedema (HAE), a human genetic disorder caused by a shortage of C1 inhibitor activity that results in an overreaction … C1 Esterase Inhibitor (Human) is composed of purified endogenous complement component-1 esterase inhibitor (hC1INH) isolated from human plasma.
Products: CİNRYZE 500 IU/5 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 2 ADET, Berinert 500Fosamprenavir
go.drugbank.com/drugs/DB01319ApprovedInvestigationalFosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: TELZIR 700 MG FİLM KAPLI TABLET, 60 ADET, TELZIR®Apalutamide
go.drugbank.com/drugs/DB11901ApprovedInvestigationalApproximately 10 to 20 % of prostate cancer cases are castration-resistant, and up to 16% of these patients show no evidence of cancer metastasis at the time of castration-resistant diagnosis [L1295]. … In a randomized trial, the median metastasis-free survival for patients taking apalutamide was 40.5 months compared to 16.2 months for patients taking a placebo [L1295].
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsProducts: ERLEADA ®TABLETAS RECUBIERTAS 60 MGDifluprednate
go.drugbank.com/drugs/DB06781ApprovedInvestigationalDifluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: DİFLUNAT POMAT, 20 G, EPITOPIC POMAT %0,05, 20 GPentostatin
go.drugbank.com/drugs/DB00552ApprovedInvestigationalA potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index, Heterocyclic Compounds, 1-RingProducts: CIPROFLOXACINO TABLETAS RECUBIERTAS 500 MG.Mucopolysaccharidosis Type IVA
go.drugbank.com/conditions/DBCOND0060256Drugs: Elosulfase alfaSynonyms: MPS IV-A-Mucopolysaccharidosis IV-A, Morquio A DiseaseCobalt
go.drugbank.com/drugs/DB14574ApprovedWithdrawnA trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments.
Products: Cobalt - Liq. 29.5 Mcg/mlIocetamic acid
go.drugbank.com/drugs/DB09403ApprovedIocetamic acid is a diagnostic aid (radiopaque medium)
Categories: X-Ray Contrast Media, Iodinated, Watersoluble, Hepatotropic X-Ray Contrast MediaProducts: CHOLEBRINE 750 MG (MEDIO DE CONTRASTE RADIOLOGICO)Teniposide
go.drugbank.com/drugs/DB00444ApprovedInvestigationalTeniposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Teniposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. … Teniposide acts primarily in the G2 and S phases of the cycle.
Synonyms: 4'-demethylepipodophyllotoxin 9-(4,6-O-(R)-2-thenylidene-beta-D-glucopyranoside)International brands: Bang LaiDimercaptosuccinic acid
go.drugbank.com/drugs/DB14089ApprovedInvestigationalCategories: Compounds used in a research, industrial, or household settingProducts: MON.DMSA KIT 1 MG IV ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 5 ADET