Search
Cyclic adenosine monophosphate
go.drugbank.com/drugs/DB02527InvestigationalCyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).
Categories: Heterocyclic Compounds, 2-RingSynonyms: 3',5'-cyclic AMP, Adenosine 3',5'-phosphateAminacrine
go.drugbank.com/drugs/DB11561InvestigationalA highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as an intracellular pH indicator.
Categories: Heterocyclic Compounds, 3-Ring, Compounds used in a research, industrial, or household settingSynonyms: 5-aminoacridine, 10-amino-5-azaanthraceneA-674563
go.drugbank.com/drugs/DB08568ExperimentalCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingSynonyms: (alphaS)-alpha-(((5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl)oxy)methyl)benzeneethanamineTubocurarine
go.drugbank.com/drugs/DB01199ApprovedWithdrawn[A216008] Tubocurarine is a benzylisoquinoline derivative and shares this structural backbone with a number of plant-derived alkaloids, including [morphine] and [papaverine]. … Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid.
Categories: Heterocyclic Compounds, 2-RingSynonyms: d-tubocurarine, 7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraraniumCyclic GMP
go.drugbank.com/drugs/DB02315ExperimentalCyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. … It is a cellular regulatory agent and has been described as a second messenger.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 3',5'-cyclic GMP, Guanosine 3',5'-cyclic phosphateATH434
go.drugbank.com/drugs/DB16965ApprovedInvestigationalSynonyms: 5,7-dichloro-2-((ethylamino)methyl)-8-hydroxy-3-methylquinazolin-4(3h)-oneCategories: Heterocyclic Compounds, 2-RingAminoimidazole carboxamide
go.drugbank.com/drugs/DB06143InvestigationalSynonyms: 5-Aminoimidazol-4-carboxamide, 5-Aminoimidazole-4-carboxamideCategories: Heterocyclic Compounds, 1-RingN-[Isoleucinyl]-N'-[adenosyl]-diaminosufone
go.drugbank.com/drugs/DB01755ExperimentalSynonyms: 5'-Deoxy-5'-[(L-isoleucylsulfamoyl)amino]adenosine, N-[Isoleucinyl]-N'-[adenosyl]-diaminosufonePralatrexate
go.drugbank.com/drugs/DB06813ApprovedInvestigationalPralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. … [A246703] As such, pralatrexate is thought to have a better therapeutic window compared to other antifolate analogs due to the novel target of RFC.
Categories: Heterocyclic Compounds, 2-RingSynonyms: N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid, (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acidVandetanib
go.drugbank.com/drugs/DB05294ApprovedInvestigationalOn April 6 2011, vandetanib was approved by the FDA to treat nonresectable, locally advanced, or metastatic medullary thyroid cancer in adult patients. … Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation with the potential for use in a broad range of tumour types.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-4-quinazolinamine, N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine