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Sodium fluorophosphate
go.drugbank.com/drugs/DB09484ApprovedInvestigationalSodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
Mixtures: Luster Premium White AM/PMProducts: Go Smile PM, Ett HojakdoSelumetinib
go.drugbank.com/drugs/DB11689ApprovedInvestigationalThe novel MEK 1/2 inhibitor, selumetinib, was initially approved solely for the treatment of pediatric patients with Neurofibromatosis type 1 (NF-1) and symptomatic, inoperable plexiform neurofibromas (PN
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesAluminum chlorohydrate
go.drugbank.com/drugs/DB11573ApprovedAluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action ...
Products: Neat Feat Roll-ON Antipersp.-deod.for FeetTemozolomide
go.drugbank.com/drugs/DB00853ApprovedInvestigational[A229848, A229858, L32033] Temozolomide is an imidazotetrazine prodrug that is stable at acidic pH but undergoes spontaneous nonenzymatic hydrolysis at neutral or slightly basic pH; these properties allow
Categories: P-glycoprotein substrates, P-glycoprotein substrates with a Narrow Therapeutic IndexAzatadine
go.drugbank.com/drugs/DB00719ApprovedWithdrawnAntihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- r...
Mixtures: NEXT-TABS, NEXT PRIMARIAIdelalisib
go.drugbank.com/drugs/DB09054ApprovedInvestigationalMore specifically, idelalisib targets P110δ, the delta isoform of the enzyme phosphatidylinositol-4,5-bisphosphate 3-kinase, also known as PI-3K. … The PI-3Ks are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesAmmonia
go.drugbank.com/drugs/DB11118ApprovedInvestigationalAmmonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal geometry. It is a colorless gas with a pungent smell, and become NH4, or ammonium ion, when in water. Although ammonia is used as a...
Lanreotide
go.drugbank.com/drugs/DB06791ApprovedInvestigationalLanreotide is a drug employed in the management of acromegaly (a hormonal condition caused by excess growth hormone) in addition to symptoms caused by neuroendocrine tumors, especially carcinoid syndrome. This drug is a long-acting analo...
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsAlbuterol
go.drugbank.com/drugs/DB01001ApprovedInvestigationalVet approvedSalbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity fo...
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: Ventolin Nebules PF Sol 5mg/2.5mlPovidone-iodine
go.drugbank.com/drugs/DB06812ApprovedInvestigationalPovidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Indu...
Mixtures: P-Care X, P-Care MProducts: Nex Iodio P2, JOD POLYVID WUND U BRA I P