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Displaying results 251 - 260 of 10000 in total
  1. Drug

    Mannitol

    go.drugbank.com/drugs/DB00742
    ApprovedInvestigational

    On October 30, 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients and is currently marketed for … Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables.

    Mixtures: OSMOFUNDIN INJECTION 20%, Sag-MCategories: Compounds used in a research, industrial, or household setting
  2. Drug

    Methylphenidate

    go.drugbank.com/drugs/DB00422
    ApprovedInvestigational

    Concerta also provides a sustained 10-12 hour effect, allowing for once-daily dosing. … [A177550] Clinical findings have shown that children with ADHD have an abnormality in the dopamine transporter gene (DAT1), the D4 receptor gene (DRD-4), and/or the D2 receptor gene that may be at least

    Mixtures: MEDIKINET MR, MEDIKINET MRSynonyms: methyl phenyl(piperidin-2-yl)acetate, methyl α-phenyl-α-(2-piperidyl)acetate
  3. Drug

    LY-3499446

    go.drugbank.com/drugs/DB17486
    Investigational

    Synonyms: 1-(4-(7-(2-amino-7-fluoro-1,3-benzothiazol-4-yl)-6-chloro-8-fluoro-quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one, 2-propen-1-one, 1-(4-(7-2-amino-7-fluoro-4-benzothiazolyl)-6-chloro-8-fluoro-4-quinazolinyl)-1-piperazinyl)-
  4. Drug

    Cytarabine

    go.drugbank.com/drugs/DB00987
    ApprovedInvestigational

    It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472) … A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia.

    Synonyms: 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinoneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Calcium acetate

    go.drugbank.com/drugs/DB00258
    Approved

    It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.

    Mixtures: OSVAREN 435 MG/235 MG 180 FILM KAPLI TABLET, PROCALAMINE SISE 500 ML(SETLI)Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    [L7423] Losartan was granted FDA approval on 14 April 1995.[L7423] … Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension.

    Mixtures: EKLIPS FORT 100/25 MG FILM TABLET, TABLET, 90 ADET, Fortzaar 100 mg/25 mg FilmtablettenCategories: Angiotensin 2 Receptor Blocker, Agents Acting on the Renin-Angiotensin System
  7. Drug

    Leucovorin

    go.drugbank.com/drugs/DB00650
    ApprovedInvestigational

    [L56091, L56092] Additionally, it is used in combination with 5-fluorouracil (5-FU) to enhance therapeutic efficacy in the palliative treatment of advanced colorectal cancer and to treat megaloblastic … [A275451] It is primarily indicated for "leucovorin rescue" to diminish the hematologic and mucosal toxicity of high-dose methotrexate therapy in osteosarcoma and to treat inadvertent overdoses of folic

    Synonyms: 10-Formyl-7,8-dihydrofolic acid, N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acidMixtures: FERPLEX FOL 40 MG + 0.185 MG/15 ML ORAL ÇÖZELTİ, 10 ADET, KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 10 FLK.
  8. Drug

    Sitagliptin

    go.drugbank.com/drugs/DB01261
    ApprovedInvestigational

    Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256 … The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255].

    Mixtures: JANUMET 50 MG/1000 MG FILM KAPLI TABLET, 56 ADET, VELMETIA 50/1000 MG FILM KAPLI TABLET, 56 ADETCategories: Drugs Used in Diabetes, Cytochrome P-450 Substrates
  9. Drug

    Morphine

    go.drugbank.com/drugs/DB00295
    ApprovedInvestigational

    Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. … Morphine was granted FDA approval in 1941.[L12114]

    Synonyms: (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol, (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Cefixime

    go.drugbank.com/drugs/DB00671
    ApprovedInvestigational

    [A262995] Third-generation cephalosporins are often a first-line therapy against certain bacterial infections. … [A263026] However, cefixime is not recommended as a first-line of treatment for uncomplicated urogenital, anorectal, or pharyngeal gonorrhea because cefixime does not provide the same bactericidal effect

    Mixtures: INNOCEF PLUS 100/62.5 MG SASE, 20 ADET, MOLCEF PLUS 100/62.5 MG FILM KAPLI TABLET, 20 ADETCategories: Heterocyclic Compounds, 2-Ring