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Displaying results 2591 - 2600 of 10000 in total
  1. Drug

    (6S)-N-[(2S,3R,6R,7R)-3-(Acetyloxymethyl)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]octan-7-yl]-6-[(2-aminoacetyl)amino]-7-hydroxy-7-oxoheptanimidate

    go.drugbank.com/drugs/DB04488
    Experimental

    Synonyms: (6S)-N-[(2S,3R,6R,7R)-3-(Acetyloxymethyl)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]octan-7-yl]-6-[(2-aminoacetyl)amino]-7-hydroxy-7-oxoheptanimidate
  2. Drug

    Levothyroxine

    go.drugbank.com/drugs/DB00451
    ApprovedInvestigational

    [F4633] T<sub>4</sub> and T<sub>3</sub> act on nearly every cell of the body, but have a particularly strong effect on the cardiac system. … deiodination (by type I or type II 5′-deiodinases)[A179941] into its active metabolite T<sub>3</sub>.

    Mixtures: SYNTHROID® 112 MCG TABLETAS, BITIRON 50 MCG/12.5 MCG TABLET, 100 ADETCategories: UGT1A1 Substrates with a Narrow Therapeutic Index, P-glycoprotein inducers
  3. Drug

    Tulmimetostat

    go.drugbank.com/drugs/DB19446
    Investigational

    Tulmimetostat is under investigation in clinical trial NCT05467748 (EZH2 Inhibitor, Tulmimetostat, and PD-1 Blockade for Treatment of Advanced Non-small Cell Lung Cancer).

    Synonyms: (2R)-7-chloro-2-[trans-4-(3-methoxyazetidin-1-yl)cyclohexyl]-2,4-dimethyl-N-{[6-methyl-4-(methylsulfanyl)-2-oxo-1,2-dihydropyridin-3-yl]methyl}-2H-1,3-benzodioxole-5-carboxamide, 1,3-Benzodioxole-5-carboxamide, 7-chloro-N-[[1,2-dihydro-6-methyl-4-(methylthio)-2-oxo-3-pyridinyl]methyl]-2-[trans-4-(3-methoxy-1-azetidinyl)cyclohexyl]-2,4-dimethyl-, (2R)-
  4. Drug

    Mizagliflozin

    go.drugbank.com/drugs/DB19036
    Investigational

    Mizagliflozin is under investigation in clinical trial NCT05721729 (Effect of Mizagliflozin Repeat Dosing on Adverse Events and Postprandial Glucose Excursions).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Propanamide, 3-((3-(4-((3-(.beta.-d-glucopyranosyloxy)-5-(1-methylethyl)-1h-pyrazol-4-yl)methyl)-3-methylphenoxy)propyl)amino)-2,2-dimethyl-, 3-((3-(4-((3-(.beta.-d-glucopyranosyloxy)-5-(propan-2-yl)-1h-pyrazol-4-yl)methyl)-3-methylphenoxy)propyl)amino)-2,2-dimethylpropanamide
  5. Drug

    Oxfendazole

    go.drugbank.com/drugs/DB11446
    InvestigationalVet approved

    Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: (5-(phenylsulfinyl)-1H-benzimidazol-2-yl)carbamic acid methyl ester, 5-phenylsulfinyl-2-carbomethoxyaminobenzimidazole
  6. Drug

    Robalzotan

    go.drugbank.com/drugs/DB06538
    Experimental

    Synonyms: (R)-3-(Dicyclobutylamino)-8-fluoro-5-chromancarboxamideCategories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT1 Receptor Antagonists
  7. Drug

    Erbumine

    go.drugbank.com/drugs/DB18019
    Investigational

    Synonyms: 1-((3-chloro-2-fluorophenyl)methyl)-4-((3-fluoro-6-((5-methyl-1h-pyrazol-3-yl)amino)-2-pyridinyl)methyl)-2-methyl-, (2r,4r)-,4-piperidinecarboxylic acid, 4-piperidinecarboxylic acid, 1-((3-chloro-2-fluorophenyl)methyl)-4-((3-fluoro-6-((5-methyl-1h-pyrazol-3-yl)amino)-2-pyridinyl)methyl)-2-methyl-, (2r,4r)-Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Ninvosudil

    go.drugbank.com/drugs/DB08756
    Investigational

    Y-27632 is an inhibitor of Rho-associated protein kinase. It inhibits calcium sensitization to affect smooth muscle relaxation.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide, (R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide
  9. Drug

    ASI402

    go.drugbank.com/drugs/DB06373
    Investigational

    ASI402 is a monoclonal antibody that targets an aberrantly glycosylated antigen Mucin 1. It is being investigated in cancers.

    Synonyms: IMMUNOGLOBULIN G1, ANTI-(HUMAN EPISIALIN) (HUMAN-MOUSE MONOCLONAL HMFG-1 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL HMFG-1, DIMER, IMMUNOGLOBULIN G1, ANTI-(HUMAN EPISIALIN) (MOUSE MONOCLONAL HMFG-1 .GAMMA.1-CHAIN), DISULFIDE WITH MOUSE MONOCLONAL HMFG-1, DIMER
  10. Drug

    Sevasemten

    go.drugbank.com/drugs/DB18983
    Investigational

    Sevasemten is under investigation in clinical trial NCT05291091 (Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON)).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 2-[(5-fluoropyridin-3-yl)methyl]-6-[2-(2,2,2- trifluoroethoxy)pyrimidin-5-yl]pyridazin-3(2H)-one