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Indigotindisulfonic acid
go.drugbank.com/drugs/DB11577ApprovedInvestigational[A251405] Indigotindisulfonic acid is used in clinical medicine to determine patency of the urinary collecting system, and to assist in specific surgical procedures such as cystourethroscopy. … [A32490,A32491,A32492] In 2022, the FDA approved the intravenous use of indigotindisulfonate sodium to aid in visualizing ureter integrity in cystoscopic assessments.[L42600]
Diprenorphine
go.drugbank.com/drugs/DB01548IllicitInvestigationalVet approvedA narcotic antagonist similar in action to naloxone. It is used to remobilize animals after etorphine neuroleptanalgesia and is considered a specific antagonist to etorphine. [PubChem]
Interferon alfa-n3
go.drugbank.com/drugs/DB00018ApprovedPurified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Mepolizumab
go.drugbank.com/drugs/DB06612ApprovedInvestigationalThis indication was subsequently expanded to cover EGPA on December 12, 2017, and HES on September 25, 2020.[L16518] … Activated eosinophils further stimulate an inflammatory response and also induce tissue lesions and promote fibrosis, all of which contribute to the multifactorial symptomatology of hypereosinophilic diseases
Fencamfamin
go.drugbank.com/drugs/DB01463ApprovedIllicitWithdrawnIt is especially useful in patients with chronic conditions due to its favourable safety profile. … It is around half the potency of [dexamphetamine], and is prescribed at a dose of 10-60mg, although abusers of the drug tend to rapidly develop tolerance and escalate their dose.
Benzthiazide
go.drugbank.com/drugs/DB00562ApprovedThiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. … Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics).
Streptozocin
go.drugbank.com/drugs/DB00428ApprovedInvestigationalIt is used as an antineoplastic agent and to induce diabetes in experimental animals.
Relugolix
go.drugbank.com/drugs/DB11853ApprovedInvestigational[L27996] In addition to its relative ease-of-use, relugolix was shown to be superior in the depression of testosterone levels when compared to [leuprolide], another androgen deprivation therapy used in … antagonist approved for the treatment of prostate cancer - similar therapies such as [degarelix] require subcutaneous administration - and therefore provides a less burdensome therapeutic option for patients who
Demecarium
go.drugbank.com/drugs/DB00944ApprovedThe outflow of the aqueous humor is facilitated, which leads to a reduction in intraocular pressure. … Demecarium is an indirect-acting parasympathomimetic agent that is used to treat glaucoma. It is a cholinesterase inhibitor or an anticholinesterase.
Gastric intrinsic factor
go.drugbank.com/drugs/DB09349Approvedis currently in the marketed (but unapproved) product Hematogen in combination with cyanocobalamin (synthetic Vitamin B12), ferrous fumarate, and ascorbic acid for the treatment of anemias responsive to