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Displaying results 2601 - 2610 of 8411 in total
  1. Drug

    FM-VP4

    go.drugbank.com/drugs/DB05449
    Investigational

    Additional experiments suggest that FM-VP4 can reduce plasma LDL cholesterol levels and triglyceride levels, reduce weight gain and exert a anti-atherosclerosis effect.

  2. Drug

    Sebetralstat

    go.drugbank.com/drugs/DB18305
    ApprovedInvestigational

    Hereditary angioedema (HAE) is a rare genetic disease that causes sudden, painful swelling episodes in various body locations that can be life-threatening, particularly when affecting the throat [L53533

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  3. Drug

    Magnesium acetate

    go.drugbank.com/drugs/DB13996
    Approved

    Synonyms: acetato de magnesio, Magnesium di(acetate)Mixtures: ELETTROLITICA BILANCIATA DI MANTENIMENTO CON GLUCOSIO BAXTER, ELETTROLITICA BILANCIATA DI MANTENIMENTO CON GLUCOSIO BAXTER
  4. Drug

    Pimavanserin

    go.drugbank.com/drugs/DB05316
    ApprovedInvestigational

    In fact, pimavanserin is the first antipsychotic drug without D<sub>2</sub> blocking activity. … Pimavanserin is an atypical antipsychotic indicated for the treatment of psychiatric disorders.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Lazertinib

    go.drugbank.com/drugs/DB16216
    ApprovedInvestigational

    Lazertinib is an oral, third-generation, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  6. Drug

    ABBV-514

    go.drugbank.com/drugs/DB17586
    Investigational

    ABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor.[L45464]

  7. Drug

    Albendazole

    go.drugbank.com/drugs/DB00518
    ApprovedInvestigationalVet approved

    A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: CHAMPS D-WORMS SUSPENSION 200MG/5ML, CHAMPS D-WORMS 200 MG CHOCOLATE FLAVOUR CHEWABLE TABLET
  8. Drug

    Amoxapine

    go.drugbank.com/drugs/DB00543
    Approved

    The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amoxapine does not affect mood or arousal, but may cause sedation.

    Categories: Dopamine D2 Receptor Antagonists, P-glycoprotein inhibitors
  9. Drug

    Creatine

    go.drugbank.com/drugs/DB00148
    ApprovedInvestigationalNutraceutical

    An amino acid derivative that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.

  10. Drug

    Tranylcypromine

    go.drugbank.com/drugs/DB00752
    ApprovedInvestigational

    An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine).

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2A6 InhibitorsSynonyms: dl-tranylcypromine, trans-DL-2-Phenylcyclopropylamine