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Methysergide
go.drugbank.com/drugs/DB00247ApprovedWithdrawnIt antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. … Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome.
Synonyms: (+)-N-(1-(Hydroxymethyl)propyl)-1-methyl-D-lysergamide, N-(1-(Hydroxymethyl)propyl)-1-methyl-dextro-(+)-lysergamideToremifene
go.drugbank.com/drugs/DB00539ApprovedInvestigational[A256928] Toremifene possesses tissue-specific actions: it has estrogenic (agonist) activity on the cardiovascular system and on bone tissue and it has weak estrogenic effects on uterine tissue, however … , it also has antiestrogenic (estrogen-antagonist) activity on breast tissue.
Lotilaner
go.drugbank.com/drugs/DB17992ApprovedInvestigationalVet approved[A260741] On July 25, 2023, lotilaner was approved by the FDA for the treatment of Demodex blepharitis, making it the first and only approved therapeutic for this condition.[L47551] … [L47546] Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.
Synonyms: 2-thiophenecarboxamide, 5-((5s)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl)-3-methyl-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-, 3-methyi-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-((55)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)thiophene-2-carboxamidePerflutren
go.drugbank.com/drugs/DB00556ApprovedInvestigationalThe difference in density between the gas-filled bubbles and the blood around them creates an increased level of contrast visible in the resulting ultrasound image. … During echocardiography, activated Perflutren enhances images of the inner edges or borders of the heart, producing an improved image that may enable physicians to better diagnose patients.
Categories: Compounds used in a research, industrial, or household settingProducts: CIPROFLOXACINO TABLETAS X 500 MG, Definity RTMeclizine
go.drugbank.com/drugs/DB00737ApprovedInvestigationalIt is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular system diseases. … It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects.
Products: Dramamine - N, Jet-Avert Motion Sickness AidSIG-001
go.drugbank.com/drugs/DB17826InvestigationalSIG-001 is a cultured human retinal pigment epithelial cell line (ARPE-19) genetically modified with a non-viral vector to express B domain deleted human factor VIII protein, encapsulated within two-layer
Ox bile extract
go.drugbank.com/drugs/DB14016ApprovedMixtures: İNTESTİNOL 59,4 MG/21,3 MG/71,1 MG KAPLI TABLET, 120 ADET, İNTESTİNOL 59,4 MG/21,3 MG/71,1 MG KAPLI TABLET, 60 ADETEVT 302
go.drugbank.com/drugs/DB06057InvestigationalEVT 302 is an orally active, potent, highly selective and reversible inhibitor of MAO-B. It is in the development for smoking cessation, and potential for disease modification in Alzheimer's disease.
Periciazine
go.drugbank.com/drugs/DB01608ApprovedIt is a sedative phenothiazine with weak antipsychotic properties. It also has adrenolytic, anticholinergic, metabolic and endocrine effects and an action on the extrapyramidal system. … It is used as an adjunctive medication in some psychotic patients, for the control of residual prevailing hostility, impulsiveness and aggressiveness.
Oxprenolol
go.drugbank.com/drugs/DB01580ApprovedWithdrawnA beta-adrenergic antagonist used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety.